已验证抗体 * 退换有保障
Rabbit Polyclonal Antibody to ANK3
Catalog No.：FA03903 【Specification】
Antibody Type: Primary antibody
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Synthetic peptide of human ANK3
Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.
【Description】
Ankyrins are a family of proteins that are believed to link the integral membraneproteins to the underlying spectrin-actin cytoskeleton and play key roles in activitiessuch as cell motility, activation, proliferation, contact, and the maintenance ofspecialized membrane domains. Multiple isoforms of ankyrin with different affinitiesfor various target proteins are expressed in a tissue-specific, developmentallyregulated manner. Most ankyrins are typically composed of three structuraldomains: an amino-terminal domain containing multiple ankyrin repeats; a centralregion with a highly conserved spectrin binding domain; and a carboxy- terminalregulatory domain which is the least conserved and subject to variation. Ankyrin 3is an immunologically distinct gene product from ankyrins 1 and 2, and wasoriginally found at the axonal initial segment and nodes of Ranvier of neurons in thecentral and peripheral nervous systems. Multiple transcript variants encodingdifferent isoforms have been found for this gene.
【Application】
For Research Only-Time Saved, Science Advanced苏州丰度蛋白生物技术有限公司（www.fedprotein.com)
The image is immunohistochemistry of paraffin-
embedded Human cervical cancer tissue using
(ANK3 Antibody) at dilution 1/50. (Original
magnification: ×200)