Product Name：Dulaglutide
CAS No.：923950-08-7
Synonyms：Dulaglutide - solution in PBS；杜拉鲁肽
Catalog No.：218P075
Brand：HongTide（上海鸿肽生物）
Description：杜拉鲁肽是新型长效GLP-1R激动剂多肽，序列中包含31个氨基酸，由两个具有DPP-4 抑制作用的GLP-1类似物和人免疫球蛋白重链IgG4-Fc 片段融合得到，在临床表现中其活性与内源性GLP-1相似，半衰期为5天，能有效延缓肾脏的清除作用。FDA于2014 年9 月批准杜拉鲁肽皮下注射液上市。欧盟委员会于2014年12月批准杜拉鲁肽皮下注射液在欧洲上市。
Dulaglutide is a novel long-acting GLP-1R agonist peptide with a sequence containing 31 amino acids. It is obtained by fusion of two GLP-1 analogues with DPP-4 inhibition and human immunoglobulin heavy chain IgG4-Fc fragments. In clinical manifestations, its activity is similar to endogenous GLP-1, with a half-life of 5 days, and can effectively delay renal clearance. The FDA approved the marketing of Dulaglutide subcutaneous injection in September 2014. The European Commission approved the marketing of Dulaglutide subcutaneous injection in Europe in December 2014.
Purity (HPLC) ≥95.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | HGEGTFTSDVSSYLEEQAAKEFIAWLVKGGG |
Sequence(3-letter code) | H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Glu-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Gly-Gly-OH |
Peptide Structure | 
|
Molecular Formula | C149H221N37O49 |
Molecular Weight | 3314.62 |
订购联系方式：
上海鸿肽生物科技有限公司
手机： +86-18018095145 （同微信号）
QQ: 3259098395
邮箱：sales1@hongtide.com
关键字： 923950-08-7;Dulaglutide;杜拉鲁肽;Dulaglutide - soluti;多肽;
上海鸿肽生物科技有限公司（简称：鸿肽生物）是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖：定制多肽、目录多肽、氨基酸衍生物、小分子化合物；公司自成立以来，秉持“用质量作船， 以服务为帆，为科研服务”的企业理念，为国内外众多科研工作者提供了优质的服务及产品。