Host:Rabbit
Target Protein:ATF4
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:468
Swiss Prot:P18848
Source:KLH conjugated synthetic peptide derived from human ATF4:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-1000)
IHC-P(1:50-200)
IHC-F(1:50-200)
Flow-Cyt(1:50)
ICC(1:50)
IF(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用！
关键字： CREB-2;CREB2;CREB2;CREB 2;TAXREB67;
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