Host:Rabbit
Target Protein:Integrin alpha 4
IR:Immunogen Range:551-650/1032
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3676
Swiss Prot:P13612
Source:KLH conjugated synthetic peptide derived from human Integrin alpha 4:551-650/1032
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Flow-Cyt(1μg/Test)
Cross Reactive Species:Human
Mouse
Rat
Cow
Horse
Rabbit
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： CD49D;CD49d;CD 49d;CDw49d;IA4;MGC90518;VLA ;ITA4_HUMAN;
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