Rabbit Anti-FTO Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:FTO
IR:Immunogen Range:165-265/505
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:79068
Swiss Prot:Q9C0B1
Source:KLH conjugated synthetic peptide derived from human Protein fatso:165-265/505
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Contributes to the regulation of body size and body fat accumulation.
Tissue specificity: Ubiquitously expressed, with relatively high expression in adrenal glands and brain; especially in hypothalamus and pituitary.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit
Sheep
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： FTO;Alpha-ketoglutarate;dioxygenase ;FTO;Fat mass and obesity;Protein fatso.;脂肪堆积和肥胖相关蛋白抗体;FTO_HUMAN;
上海沪震实业有限公司是一家集研发、生产和销售于一体的生命科学实验室产品生物科技企业。主营产品：试剂盒，ELISA试剂盒，抗体，重组蛋白，血清，胎牛血清，细胞，原代细胞 细胞培养试剂，常用生化试剂。