中文名:2-溴-5-氟吡啶
英文名:2-Bromo-5-fluoropyridine
纯度:≥99%
货号:B111195
Cas号:41404-58-4
运输条件:常规运输
产品介绍:
钯催化条件下,酯α-芳基化的起始物质。生成4-吡啶基羧基哌啶(4-pyridylcarboxypiperidines)。
2-Bromo-5-fluoropyridine can be used in the synthesis of the following:
• 5-fluoro-2-phenylpyridine via Suzuki coupling reaction with phenylboronic acid
• 5-fluoro-2-(p-tolyl)pyridine via Suzuki coupling reaction with p-tolylboronic acid
It can undergo palladium-catalyzed homo-coupling reaction to give the corresponding biaryl. It can also be employed in a palladium-catayzed α-arylation of esters leading to 4-pyridylcarboxypiperidines.
避免的条件:强加热
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