中文名:4,4,4-三氟乙酰乙酸乙酯
英文名:Ethyl 4,4,4-trifluoroacetoacetate
应用:合成含氟杂环医药和农药的重要中间体,有机合成砌块。 Ethyl 4,4,4-trifluoroacetoacetate (ETFAA) is a general reagent to synthesize enantiopure trifluoromethyl-functionalized products. Applications include: · Synthesis of (S)- and (R)-α-trifluoromethyl-aspartic acid and α- trifluoromethyl-serine from chiral CF3-oxazolidines, which is derived from ETFAA. · Enantiopure synthesis of trifluoromethyl-β-amino acid derivatives. · Synthesis of (2R)-2-trifluoromethyl-2-carboxyazetidine, (R)- and (S)-trifluoromethylhomoserines from oxazolidine intermediate obtained by condensing (R)-phenylglycinol with ETFAA.
纯度:≥98%
货号:E109508
Cas号:372-31-6
存储温度:充氩
运输条件:常规运输
产品介绍:
溶于乙醇、醚、苯等溶剂。水中溶解度:10 g/l (20°C)。合成含氟杂环医药和农药的重要中间体,有机合成砌块。
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