aladdin 阿拉丁 V125336 N-羟基-N'-苯基辛二酰胺 149647-78-9 ≥99.0%

中文名：N-羟基-N'-苯基辛二酰胺

英文名：Vorinostat (SAHA, MK0683)

纯度：Moligand™，≥99%

货号：V125336

Cas号：149647-78-9

存储温度：-20°C储存

运输条件：超低温运输

产品介绍：

Suberoylanilide Hydroxamic Acid (SAHA) is a potent histone deacetylase (HDAC) inhibitor that has been shown to inhibit proliferation and cause cell cycle arrest at G1. Experiments suggest that SAHA also causes morphological changes, such as enlargement and flattening of the cytoplasm, resulting in growth inhibition. Treatment of cells with SAHA also decreases the expression of anti-apoptosis proteins Bcl-xL and survivin.

A potent HDAC inhibitor; also causes cell cycle arrest at G1

SAHA可用于研究基因调控、转录调控和细胞信号转导。

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