中文名:塞马西尼
英文名:SU5416
应用:It was used to study the mechanism of development of cerebral vasculature in zebrafish hindbrain,and study the pulmonary vascular remodeling in response to hypoxia in mouse model of pulmonary arterial hypertension.
纯度:Moligand™,≥98%(HPLC)
货号:S125835
Cas号:204005-46-9
存储温度:-20°C储存,充氩
运输条件:超低温运输
产品介绍:
Semaxanib (SU5416)是VEGFR(Flk-1/KDR)抑制剂,IC50为1.23 μM,比对PDGFRβ的抑制性高20倍,对EGFR,InsR和FGFR无活性。It was used to study the mechanism of development of cerebral vasculature in zebrafish hindbrain,and study the pulmonary vascular remodeling in response to hypoxia in mouse model of pulmonary arterial hypertension.
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