aladdin 阿拉丁 E286966 Endoxifen,抗雌激素 110025-28-0 ≥98%(HPLC)

中文名：Endoxifen,抗雌激素

英文名：(E/Z)-Endoxifen

纯度：≥98%(HPLC)

货号：E286966

Cas号：110025-28-0

存储温度：-20°C储存

运输条件：超低温运输

产品介绍：

Product description：

(E/Z)-Endoxifen is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It is a strong anti-estrogen, as it has an approximately 100-fold greater affinity for estrogen receptors than tamoxifen. As the efficient conversion of tamoxifen to endoxifen depends on CYP2D6, polymorphisms in this CYP isoform can impact the effectiveness of TMX treatment.

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