中文名：四氢小檗碱
英文名：Tetrahydroberberine
纯度：≥99%
货号：T413234
Cas号：522-97-4
存储温度：-20°C储存
运输条件：超低温运输
产品介绍：
Information
Tetrahydroberberine (Canadine) is an isoquinoline alkaloid with micromolar affinity fordopamine D2(antagonist, pKi = 6.08) and5-HT1A(agonist, pKi = 5.38) receptors but moderate to no affinity for other relevant serotonin receptors.
Targets
D2 receptor ; 5-HT1A 6.08(pKi); 5.38(pKi)
In vivo
Oral administration of THB not only resulted in significantly accelerated gastric emptying of normal rats in a bell-shaped relationship, with a maximal efficacy at a dose of 30 μg/kg, but also restored the delayed gastric emptying caused by apomorphine, which might be mediated by an antidopaminergic effect.
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关键字： CANADINE DL-FORM [MI] ; DTXCID802724 ; Isoquinolino[2,1-b]isoquinoline, 5,6,7,8,13,13a-hexahydro-2,3-methylenedioxy-9,10-dimethoxy- ; 10-METHOXY-5,8,13,13A-TETRAHYDRO-6H-[1,3]DIOXOLO[4,5-G]ISOQUINO[3,2-A]ISOQUINOLIN-9-YL METHYL ETHER
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