中文名:基于吉非替尼的 PROTAC 3
英文名:Gefitinib-based PROTAC 3
纯度:Moligand™,≥98%(HPLC),PROTAC
货号:G287801
Cas号:2230821-27-7
存储温度:-20°C储存
运输条件:超低温运输
产品介绍:
Product Introduction
Gefitinib-based PROTAC 3 which conjugates an EGFR binding element to a VHL ligand via a linker induces degradation of EGFR and mutants with DC50 of 11.7 nM and 22.3 nM in HCC827(Exon 19 del) and H3255 (L858R) cells, respectively.
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