基本描述
产品名称:Recombinant Human IL-17RA/IL-17R Protein
规格或纯度:无动物源,无载体,生物活性,ActiBioPure™,无叠氮钠,高性能,His标签,Fc标签,≥95%(SDS-PAGE)
生物活性:Measured by its ability to inhibit IL-17-induced IL-6 secretion by NIH‑3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.03‑0.1 µg/mL in the presence of 10 ng/mL recombinant human IL‑17.
纯度:>95%(SDS-PAGE)
氨基酸:33-320 aa
无载体:Yes
无动物源:Yes
Accession #:Q96F46
预测分子量:60 kDa
级别:无动物源, 无载体, 生物活性, ActiBioPure™, 无叠氮钠, 高性能, His标签, Fc标签
产品规格参数
储存缓冲液:PBS(PH7.4), containing 5% trehalose, 5% mannitol
复溶:Reconstitute in water to a concentration of 0.1-1.0 mg/ml.
储存温度:-20°C储存
运输条件:超低温运输
稳定性与储存:自收到之日起 12 个月,-20 至 -70 ℃。 1 个月,复溶后无菌条件下 2 至 8 ℃。 3 个月,复溶后无菌条件下 -20 至 -70 ℃。
功能和特点
Accession #:Q96F46
生物活性:Measured by its ability to inhibit IL-17-induced IL-6 secretion by NIH‑3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.03‑0.1 µg/mL in the presence of 10 ng/mL recombinant human IL‑17.
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Protein Bioactivity: Recombinant Human IL-17RA/IL-17R Protein (rp147441)
Recombinant Human IL-17RA/IL-17R Protein (rp147441) - Protein Bioactivity
Measured by its ability to inhibit IL-17-induced IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells. The ED₅₀ for this effect is 0.08 µg/mL in the presence of 10 ng/mL recombinant human IL-17.

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Binding ELISA: Recombinant Human IL-17RA/IL-17R Protein (rp147441)
Recombinant Human IL-17RA/IL-17R Protein (rp147441) - Binding ELISA
IL-17RA/IL-17R Protein (rp147441) was serially diluted 3-fold and coated on a Clear Polystyrene Microplate (W291037) can bind Brodalumab (anti-IL17RA) (Ab169276). The EC₅₀ for this effect is 5.5 ng/mL.

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SDS-PAGE: Recombinant Human IL-17RA/IL-17R Protein (rp147441)
Recombinant Human IL-17RA/IL-17R Protein (rp147441) - SDS-PAGE
2 μg/lane of Recombinant Human IL-17RA/IL-17R was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 91.3 kDa under reducing conditions and 208.1 kDa under non-reducing conditions.
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关键字: 重组人白细胞介素17受体蛋白 ; 重组人 IL-17RA/IL-17R 蛋白;CD217 antigen ; CD217
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