Product Name:Candidalysin
CAS No.:1906866-53-2
Synonyms:细胞溶解性肽毒素多肽
Catalog No.:218P868
Brand:HongTide(上海鸿肽生物)
Description:Candidalysin 是一种细胞溶解性肽毒素,最初从 Candida albicans 中分离出来,同时具有毒性和非毒性的特征,是由31个氨基酸组成的多肽。Candidalysin 通过与宿主细胞的上皮生长因子受体 (EGFR) 相互作用激活上皮细胞信号通路,激活基质金属蛋白酶 (MMP) 和钙离子内流,导致炎症反应和免疫细胞募集。Candidalysin 通过对宿主细胞造成膜损伤而表现出细胞毒性。
Candidalysin is a cell soluble peptide toxin originally isolated from Candida albicans, with both toxic and non-toxic characteristics. It is a peptide composed of 31 amino acids. Candidalysin activates the epithelial signaling pathway by interacting with the host cell's epithelial growth factor receptor (EGFR), activating matrix metalloproteinases (MMPs) and calcium influx, leading to inflammatory response and immune cell recruitment. Candidalysin exhibits cytotoxicity by causing membrane damage to host cells.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | SIIGIIMGILGNIPQVIQIIMSIVKAFKGNK |
Sequence(3-letter code) | H-Ser-Ile-Ile-Gly-Ile-Ile-Met-Gly-Ile-Leu-Gly-Asn-Ile-Pro-Gln-Val-Ile-Gln-Ile-Ile-Met-Ser-Ile-Val-Lys-Ala-Phe-Lys-Gly-Asn-Lys-OH |
Peptide Structure | 
|
Molecular Formula | C153H266N38O38S2 |
Molecular Weight | 3310.11 |
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本产品仅供科研使用。
关键字: 1906866-53-2;Candidalysin ;细胞溶解性肽毒素多肽;多肽;多肽合成;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。