Product Name：Candidalysin
CAS No.：1906866-53-2
Synonyms：细胞溶解性肽毒素多肽
Catalog No.：218P868
Brand：Typeptide Biotech（肽研生物）
Description：Candidalysin 是一种细胞溶解性肽毒素，最初从 Candida albicans 中分离出来，同时具有毒性和非毒性的特征，是由31个氨基酸组成的多肽。Candidalysin 通过与宿主细胞的上皮生长因子受体 (EGFR) 相互作用激活上皮细胞信号通路，激活基质金属蛋白酶 (MMP) 和钙离子内流，导致炎症反应和免疫细胞募集。Candidalysin 通过对宿主细胞造成膜损伤而表现出细胞毒性。
Candidalysin is a cell lytic peptide toxin that was initially isolated from Candida albicans and has both toxic and non-toxic characteristics. It is a peptide composed of 31 amino acids. Candidalysin activates the epithelial cell signaling pathway by interacting with the host cell's epithelial growth factor receptor (EGFR), activating matrix metalloproteinases (MMP) and calcium influx, leading to inflammatory response and immune cell recruitment. Candidalysin exhibits cytotoxicity by causing membrane damage to host cells.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | SIIGIIMGILGNIPQVIQIIMSIVKAFKGNK |
Sequence(3-letter code) | H-Ser-Ile-Ile-Gly-Ile-Ile-Met-Gly-Ile-Leu-Gly-Asn-Ile-Pro-Gln-Val-Ile-Gln-Ile-Ile-Met-Ser-Ile-Val-Lys-Ala-Phe-Lys-Gly-Asn-Lys-OH |
Peptide Structure | 
|
Molecular Formula | C153H266N38O38S2 |
Molecular Weight | 3310.11 |
订购联系方式：
南京肽研生物生物科技有限公司
手机号：19961912513(微信同号)
QQ: 2178255659
邮箱：sales@typeptide.com
联系人：顾经理
申明：本产品仅供科研使用，不得用于人体。
关键字： Candidalysin;细胞溶解性肽毒素多肽;1906866-53-2;多肽;多肽合成;
肽研生物坐落于国家级新区南京江北新区新材料产业园，是一家专业从事多肽产 品的研发、生产和销售以及多肽技术转让的高新技术企业。公司秉持“诚信、严 谨、务实”的匠人精神，持续投入研发，不断创新，致力于为科研工作者提供丰 富全面的多肽修饰类型和优质的产品。