Cynomolgus PADI4 Protein, His Tag (active enzyme)
分子别名（Synonym）
Protein-arginine deiminase type-4,HL-60 PAD,Peptidylarginine deiminase IV,Protein-arginine deiminase type IV,PADI4,EC:3.5.3.15
表达区间及表达系统（Source）
Cynomolgus PADI4 Protein, His Tag (PA4-C5143) is expressed from E. coli cells. It contains AA Met 1 - Pro 663 (Accession # A0A2K5USI5-1).
蛋白结构（Molecular Characterization）
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 76.1 kDa. The protein migrates as 70-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
内毒素（Endotoxin）
Less than 1.0 EU per μg by the LAL method.
纯度（Purity）
>90% as determined by SDS-PAGE.
制剂（Formulation）
Supplied as 0.2 μm filtered solution in 500 mM NaCl, pH8.0 with glycerol as protectant.
Contact us for customized product form or formulation.
运输（Shipping）
This product is supplied and shipped with dry ice, please inquire the shipping cost.
存储（Storage）
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
The product MUST be stored at -70°C or lower upon receipt;
-70°C for 3 months under sterile conditions.
背景（Background）
Protein arginine deiminase, type 4 (PADI4) is a calcium dependent enzyme Catalyzes the citrullination/deimination of arginine residues of proteins such as histones, thereby playing a key role in histone code and regulation of stem cell maintenance. PADI4 can interact with tumor suppressor p53 and regulate the transcriptional activity of p53. Dysregulation of PADI4 is implicated in a variety of diseases, including rheumatoid arthritis, tumor development, and multiple sclerosis.
关键字： PADI4;PADI4蛋白;PADI4重组蛋白;ACRO;百普赛斯;
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