NAPSA抗体,Mouse Monoclonal NAPSA Antibody
  • NAPSA抗体,Mouse Monoclonal NAPSA Antibody
  • NAPSA抗体,Mouse Monoclonal NAPSA Antibody
  • NAPSA抗体,Mouse Monoclonal NAPSA Antibody

NAPSA抗体 新品

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-10
QQ交谈 微信洽谈

产品详情

中文名称:NAPSA抗体英文名称:Mouse Monoclonal NAPSA Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 596 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Mouse
偶联物: 靶点: NAPSA
2025-05-10 NAPSA抗体 Mouse Monoclonal NAPSA Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 596 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB1/500 - 1/2000 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/200 - 1/1000 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/10000 Human,Mouse,Rat
   

产品详情

AliasesKAP; Kdap; NAP1; NAPA; SNAPA
Entrez GeneID9476
clone10C4B8
WB Predicted band size45.4kDa
Host/IsotypeMouse IgG1
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman,Rat
ImmunogenPurified recombinant fragment of human NAPSA (AA: 20-158) expressed in E. Coli.
FormulationPurified antibody in PBS with 0.05% sodium azide

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       Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);    


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       Western blot analysis using NAPSA mouse mAb against rat liver tissue lysate.    


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       Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using NAPSA mouse mAb with DAB staining.    


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       Immunohistochemical analysis of paraffin-embedded human liver cancer tissues using NAPSA mouse mAb with DAB staining.    


           

参考文献

以下是关于NAPSA(Napsin A)抗体的3篇文献示例及简要摘要:

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1. **文献名称**:*Napsin A and TTF-1 expression in pulmonary adenocarcinomas*

**作者**:Mukhopadhyay S, Katzenstein AL.

**摘要**:研究分析了Napsin A和TTF-1在肺腺癌中的表达模式,证实Napsin A可作为肺腺癌的特异性标志物,尤其在TTF-1阴性病例中具有互补诊断价值。

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2. **文献名称**:*Napsin A expression in renal cell carcinomas: a potential diagnostic pitfall*

**作者**:Lin F, Shi J.

**摘要**:探讨Napsin A在肾细胞癌中的异常表达,提示其在诊断中可能导致误判,强调需结合其他标志物(如PAX8)进行鉴别诊断。

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3. **文献名称**:*Utility of Napsin A in diagnostic pathology: a review*

**作者**:Bishop JA, Sharma R, Illei PB.

**摘要**:综述Napsin A抗体的应用,强调其在肺腺癌与鳞癌鉴别、转移性腺癌来源判断中的关键作用,并讨论其局限性及与其他标志物的联合使用。

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**备注**:以上文献为示例,实际引用时需核实具体来源及内容准确性。如需具体文献链接或补充,可进一步提供研究方向。

       

背景信息

NAPSA (Napsin A aspartic peptidase) is a protease enzyme primarily expressed in the lungs and kidneys, where it plays a role in proteolytic processing of proteins. In the lungs, NAPSA is involved in the maturation of surfactant protein B (SP-B), critical for respiratory function. Its expression is largely restricted to type II pneumocytes and alveolar macrophages, making it a tissue-specific marker.

NAPSA antibodies are widely used in immunohistochemistry (IHC) to identify lung adenocarcinomas, as NAPSA is highly expressed in these tumors. It serves as a diagnostic marker to differentiate primary lung adenocarcinomas from metastatic carcinomas, especially when combined with other markers like TTF-1. NAPSA positivity in renal cell carcinomas has also been reported, highlighting its broader utility in tumor subtyping.

Research into NAPSA antibodies has expanded due to their potential role in targeted therapies and molecular diagnostics. For instance, NAPSA expression may correlate with tumor differentiation and prognosis in certain cancers. However, its biological mechanisms in cancer progression remain under investigation. Antibodies against NAPSA are thus essential tools in both diagnostic pathology and exploratory research, bridging clinical applications with ongoing studies into its functional significance.

       
关键字: NAPSA抗体;NAPSA;NAPSA Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
询盘

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