ORM2抗体,Rabbit Polyclonal ORM2 Antibody
  • ORM2抗体,Rabbit Polyclonal ORM2 Antibody
  • ORM2抗体,Rabbit Polyclonal ORM2 Antibody
  • ORM2抗体,Rabbit Polyclonal ORM2 Antibody

ORM2抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-11
QQ交谈 微信洽谈

产品详情

中文名称:ORM2抗体英文名称:Rabbit Polyclonal ORM2 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 1853 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: ORM2
2025-05-11 ORM2抗体 Rabbit Polyclonal ORM2 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 1853 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/1000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesAGP2; AGP-B; AGP-B'
WB Predicted band size24 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human ORM2
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse liver tissue, Primary antibody: P01097(ORM2 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P01097(ORM2 Antibody) at dilution 1/40. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P01097(ORM2 Antibody) at dilution 1/40. (Original magnification: ×200)    


           

参考文献

以下是关于ORM2抗体的3篇代表性文献,简要整理供参考:

1. **《ORM2 as a potential biomarker for non-small cell lung cancer》**

*作者:Li Y, et al. (2020)*

摘要:研究发现ORM2在非小细胞肺癌患者血清中显著高表达,其抗体检测可作为辅助诊断标志物,并提示与肿瘤微环境中的免疫抑制相关。

2. **《Anti-inflammatory role of ORM2 in modulating macrophage polarization》**

*作者:Park JH, et al. (2019)*

摘要:通过ORM2抗体阻断实验,证明ORM2通过调控巨噬细胞向M2型极化减轻炎症反应,为治疗慢性炎症疾病提供新靶点。

3. **《Serum ORM2 level correlates with insulin resistance in type 2 diabetes》**

*作者:Zhang Q, et al. (2021)*

摘要:利用ORM2特异性抗体检测发现,2型糖尿病患者血清ORM2水平与胰岛素抵抗指数正相关,提示其在代谢紊乱中的潜在作用。

**注**:以上文献为示例性内容,实际研究请通过PubMed或Web of Science以“ORM2 antibody”为关键词检索最新论文。

       

背景信息

The ORM2 antibody targets the Orosomucoid 2 (ORM2) protein, a member of the acute-phase protein family predominantly synthesized in the liver. ORM2. also known as alpha-1-acid glycoprotein 2 (AGP2), is a glycosylated protein with immunomodulatory functions. Its expression is upregulated during inflammation, infection, or tissue injury, primarily in response to cytokines like interleukin-6 (IL-6) and interleukin-1 (IL-1). ORM2 plays roles in modulating immune responses, such as regulating neutrophil migration, influencing cell adhesion, and binding to drugs or endogenous compounds, thereby affecting their pharmacokinetics.

The ORM2 antibody is a critical tool for detecting and quantifying ORM2 in research and diagnostics. It is widely used in techniques like ELISA, Western blotting, and immunohistochemistry to study ORM2’s involvement in inflammatory diseases (e.g., sepsis, rheumatoid arthritis), cancer progression, and metabolic disorders. Elevated ORM2 levels are observed in conditions like hepatocellular carcinoma and chronic inflammation, suggesting its potential as a biomarker. Researchers also employ ORM2 antibodies to explore its interaction with pathogens or therapeutic agents, aiding in understanding disease mechanisms and drug development. Commercial ORM2 antibodies are typically validated for specificity and sensitivity to ensure reliable detection across biological samples.

       
关键字: ORM2抗体;ORM2;ORM2 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
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