CAMK1D抗体,Rabbit Polyclonal CAMK1D Antibody
  • CAMK1D抗体,Rabbit Polyclonal CAMK1D Antibody
  • CAMK1D抗体,Rabbit Polyclonal CAMK1D Antibody
  • CAMK1D抗体,Rabbit Polyclonal CAMK1D Antibody

CAMK1D抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-11
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产品详情

中文名称:CAMK1D抗体英文名称:Rabbit Polyclonal CAMK1D Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 1873 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: CAMK1D
2025-05-11 CAMK1D抗体 Rabbit Polyclonal CAMK1D Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 1873 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/1000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesCKLiK; CaM-K1; CaMKID
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human CAMK1D
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P01150(CAMK1D Antibody) at dilution 1/50. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human brain  tissue using P01150(CAMK1D Antibody) at dilution 1/50. (Original magnification: ×200)    


           

参考文献

以下是关于 **CAMK1D抗体** 的示例参考文献(注:以下内容为模拟生成,实际文献需通过学术数据库查询):

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1. **文献名称**: *"CAMK1D regulates cell cycle progression in breast cancer via phosphorylation of p27Kip1"*

**作者**: Smith A, et al.

**摘要**: 本研究利用CAMK1D特异性抗体,通过免疫沉淀和Western blot技术,揭示了CAMK1D通过磷酸化p27Kip1调控乳腺癌细胞周期进程的机制,表明其高表达与患者预后不良相关。

2. **文献名称**: *"Neuronal CAMK1D signaling modulates synaptic plasticity in hippocampal neurons"*

**作者**: Yamaguchi T, et al.

**摘要**: 通过免疫组织化学和CAMK1D抗体的靶向抑制实验,发现CAMK1D在小鼠海马神经元突触可塑性中起关键作用,可能参与学习记忆相关的信号通路。

3. **文献名称**: *"Development and validation of a high-specificity CAMK1D monoclonal antibody for diagnostic applications"*

**作者**: Lee H, et al.

**摘要**: 研究报道了一种新型CAMK1D单克隆抗体的开发,经ELISA、免疫荧光和流式细胞术验证,证实其在多种组织样本中的高特异性和灵敏度,适用于癌症早期诊断。

4. **文献名称**: *"CAMK1D expression in metabolic syndrome: Insights from adipose tissue profiling"*

**作者**: Zhang R, et al.

**摘要**: 使用CAMK1D抗体分析肥胖患者脂肪组织样本,发现CAMK1D表达与胰岛素抵抗相关,提示其可能作为代谢综合征的潜在治疗靶点。

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**建议**:实际文献可通过 **PubMed**、**Google Scholar** 或 **Web of Science** 搜索关键词 *CAMK1D antibody*、*CAMK1D function* 等获取。

       

背景信息

The CAMK1D antibody is a crucial tool for studying the calcium/calmodulin-dependent protein kinase 1 delta (CAMK1D), a serine/threonine kinase belonging to the Ca²⁺/calmodulin-dependent protein kinase (CAMK) family. CAMK1D is encoded by the CAMK1D gene and plays a role in calcium-mediated signaling pathways, regulating cellular processes such as gene transcription, cell cycle progression, and metabolism. It is activated by calcium/calmodulin binding and further phosphorylated by upstream kinases like CAMKK, enabling its full enzymatic activity. CAMK1D is expressed in various tissues, including the brain, pancreas, and immune cells, and has been implicated in diseases such as cancer, diabetes, and neurological disorders.

The CAMK1D antibody is specifically designed to detect endogenous CAMK1D protein levels in applications like Western blotting, immunohistochemistry, and immunofluorescence. Researchers use it to investigate CAMK1D's expression patterns, post-translational modifications (e.g., phosphorylation at Thr180), and interactions within signaling cascades. Validated antibodies typically target epitopes within the kinase domain or regulatory regions, ensuring specificity by distinguishing CAMK1D from closely related isoforms (e.g., CAMK1. CAMK1G). Its development supports mechanistic studies of CAMK1D's role in cellular responses to calcium fluctuations, metabolic regulation, and pathological conditions, making it essential for both basic research and therapeutic target validation.

       
关键字: CAMK1D抗体;CAMK1D;CAMK1D Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
普通会员
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
询盘

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