The FMNL1 (Formin-like 1) antibody is a tool used to study the function and expression of FMNL1. a member of the formin family of proteins involved in cytoskeletal regulation. FMNL1 plays a critical role in actin polymerization, a process essential for cell motility, cytokinesis, and intracellular trafficking. It is particularly implicated in immune cell function, cancer cell invasion, and endothelial barrier maintenance. Dysregulation of FMNL1 has been linked to pathologies such as cancer metastasis, chronic inflammation, and vascular disorders.
FMNL1 antibodies are designed to detect specific epitopes of the protein, enabling researchers to investigate its localization, expression levels, and interactions in various biological contexts. These antibodies are widely used in techniques like Western blotting, immunofluorescence, and immunohistochemistry. Monoclonal and polyclonal variants are available, each offering distinct advantages in specificity and sensitivity.
Research utilizing FMNL1 antibodies has shed light on its role in diseases. For example, elevated FMNL1 expression correlates with aggressive tumor behavior, suggesting its potential as a biomarker or therapeutic target. In immunology, FMNL1 modulates leukocyte migration, influencing inflammatory responses. Ongoing studies aim to clarify its molecular mechanisms and therapeutic relevance, driving demand for reliable antibodies to support basic and translational research.