HSD17B6抗体,Rabbit Polyclonal HSD17B6 Antibody
  • HSD17B6抗体,Rabbit Polyclonal HSD17B6 Antibody
  • HSD17B6抗体,Rabbit Polyclonal HSD17B6 Antibody
  • HSD17B6抗体,Rabbit Polyclonal HSD17B6 Antibody

HSD17B6抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-11
QQ交谈 微信洽谈

产品详情

中文名称:HSD17B6抗体英文名称:Rabbit Polyclonal HSD17B6 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 1958 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: HSD17B6
2025-05-11 HSD17B6抗体 Rabbit Polyclonal HSD17B6 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 1958 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/1000-1/2000 Human,Mouse,Rat
   

产品详情

AliasesHSE; RODH; SDR9C6
WB Predicted band size36 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human HSD17B6
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse liver tissue, Primary antibody: P01454(HSD17B6 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute    


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       The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P01454(HSD17B6 Antibody) at dilution 1/20. (Original magnification: ×200)    


           

参考文献

以下是关于HSD17B6抗体的3篇代表性文献的简要总结(注:文献信息为模拟示例,非真实存在):

1. **文献名称**: *"HSD17B6 expression in prostate cancer and its role in androgen metabolism"*

**作者**: Smith A, et al.

**摘要**: 该研究利用HSD17B6特异性抗体,通过免疫组化和Western blot技术,发现HSD17B6在前列腺癌组织中高表达,并证实其通过调控双氢睾酮(DHT)的合成促进肿瘤进展。

2. **文献名称**: *"Characterization of HSD17B6 antibody specificity in hepatic steroidogenic pathways"*

**作者**: Chen L, et al.

**摘要**: 文章验证了一种新型HSD17B6单克隆抗体的特异性,证明其在人肝组织中对HSD17B6蛋白的高效检测能力,并揭示该酶在类固醇激素代谢中的关键作用,尤其是与胆汁酸合成的关联。

3. **文献名称**: *"HSD17B6 as a potential biomarker in breast cancer: Insights from antibody-based assays"*

**作者**: Gupta R, et al.

**摘要**: 研究使用HSD17B6抗体进行乳腺癌组织芯片分析,发现HSD17B6表达与雌激素受体阴性亚型相关,提示其可能作为预后标志物及治疗靶点。

4. **文献名称**: *"Functional analysis of HSD17B6 knockout mice using targeted antibody validation"*

**作者**: Tanaka K, et al.

**摘要**: 通过构建HSD17B6基因敲除小鼠模型,结合抗体免疫荧光技术,证明该酶在睾丸和肾上腺中的定位,并揭示其缺失导致雄激素代谢紊乱的表型。

建议通过PubMed或Google Scholar检索真实文献时使用关键词 **"HSD17B6 antibody"** 或 **"HSD17B6 function"** 获取最新研究。

       

背景信息

The HSD17B6 antibody is a tool used to detect and study the hydroxysteroid 17-beta dehydrogenase 6 (HSD17B6) enzyme, which belongs to the 17β-hydroxysteroid dehydrogenase (17β-HSD) family. This enzyme plays a role in steroid metabolism, particularly in the conversion of inactive steroid precursors to active forms. HSD17B6 is involved in androgen biosynthesis, catalyzing reactions such as the conversion of androstanediol to dihydrotestosterone (DHT) and participating in retinol metabolism. Its expression is observed in tissues like the liver, prostate, and testes, linking it to hormonal regulation and metabolic pathways.

Researchers utilize HSD17B6 antibodies in techniques like Western blotting, immunohistochemistry, and immunofluorescence to investigate the enzyme's localization, expression levels, and role in physiological or pathological processes. Studies focus on its implications in hormone-dependent cancers (e.g., prostate cancer), endocrine disorders, and metabolic diseases. The antibody aids in understanding how HSD17B6 influences steroid hormone balance, cellular proliferation, and disease progression. Additionally, HSD17B6's interaction with lipid metabolism and bile acid synthesis has sparked interest in its broader metabolic functions. Validating antibody specificity is critical to ensure accurate detection, given the structural similarities among 17β-HSD family members. Overall, the HSD17B6 antibody serves as a key reagent in exploring steroid biology and its clinical associations.

       
关键字: HSD17B6抗体;HSD17B6;HSD17B6 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
询盘

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