THAP4抗体,Rabbit Polyclonal THAP4 Antibody
  • THAP4抗体,Rabbit Polyclonal THAP4 Antibody
  • THAP4抗体,Rabbit Polyclonal THAP4 Antibody
  • THAP4抗体,Rabbit Polyclonal THAP4 Antibody

THAP4抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-11
QQ交谈 微信洽谈

产品详情

中文名称:THAP4抗体英文名称:Rabbit Polyclonal THAP4 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 2101 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: THAP4
2025-05-11 THAP4抗体 Rabbit Polyclonal THAP4 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 2101 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesPP238; CGI-36
WB Predicted band size63 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human THAP4
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 80 μg, Lane: 293T cell, Primary antibody: P01886(THAP4 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P01886(THAP4 Antibody) at dilution 1/30. (Original magnification: ×200)    


           

参考文献

以下是关于THAP4抗体的3篇参考文献示例(内容为模拟概括,具体文献需根据实际检索验证):

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1. **文献名称**: **"Development of a Monoclonal Antibody Specific to THAP4 for Epigenetic Studies"**

**作者**: Smith A et al.

**摘要**: 描述了针对人THAP4蛋白的单克隆抗体的开发,通过重组蛋白免疫小鼠获得抗体,验证了其在Western blot和免疫沉淀中的特异性,并应用于染色质结合实验中研究THAP4的表观遗传调控作用。

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2. **文献名称**: **"THAP4 Antibody Validation in Neural Stem Cell Differentiation"**

**作者**: Lee B et al.

**摘要**: 本文验证了一种商业THAP4抗体在神经干细胞模型中的应用,通过CRISPR敲除实验证实抗体特异性,发现THAP4在分化过程中表达上调,提示其可能参与神经发育调控。

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3. **文献名称**: **"THAP4 Interaction with p53: A Study Using Custom Polyclonal Antibodies"**

**作者**: Gupta R et al.

**摘要**: 利用自制的THAP4多克隆抗体(抗原为C端肽段),通过免疫共沉淀和质谱分析揭示了THAP4与p53的相互作用,为研究其在DNA损伤应答中的功能提供了工具。

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**注意事项**:

- 实际文献需通过PubMed、Google Scholar等平台以关键词“THAP4 antibody”或“anti-THAP4”检索。

- 部分研究可能未在摘要中明确提及抗体细节,需查阅方法学部分。

- 抗体供应商(如Abcam、CST)的技术手册可能引用相关文献,可参考其官网资料。

建议结合具体研究需求进一步筛选高影响力或近期发表的文献。

       

背景信息

The THAP4 antibody is a tool used to detect THAP4 (THAP domain-containing protein 4), a member of the THAP family of proteins characterized by a conserved N-terminal THAP domain, a zinc-coordinating motif involved in DNA binding. THAP4 is encoded by the *THAP4* gene in humans and is implicated in transcriptional regulation, chromatin remodeling, and cellular processes such as proliferation and apoptosis. Though less studied than other THAP proteins (e.g., THAP1 or THAP9), THAP4 is suggested to function as a transcription factor or epigenetic modulator, potentially interacting with protein complexes to regulate gene expression. Its biological roles remain under investigation, with possible links to cancer, neurodevelopment, and metabolic pathways.

THAP4 antibodies are primarily utilized in research to study protein expression, localization, and interactions via techniques like Western blotting, immunohistochemistry, and immunofluorescence. These antibodies are critical for validating THAP4 expression in cell lines or tissues, assessing its role in disease models, or exploring its molecular mechanisms. Commercial THAP4 antibodies are typically raised against specific epitopes, often in rabbits or mice, and require validation for specificity and sensitivity. Researchers should verify antibody performance using knockout controls or siRNA-mediated knockdown to minimize off-target signals. Current challenges include limited data on THAP4’s precise physiological functions and a scarcity of standardized reagents, highlighting the need for further studies to elucidate its contributions to health and disease.

       
关键字: THAP4抗体;THAP4;THAP4 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
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