The EFNB2 (Ab-330) antibody is a monoclonal antibody specifically designed to target Ephrin-B2 (EFNB2), a member of the ephrin family of transmembrane ligands that interact with Eph receptor tyrosine kinases. EFNB2 plays critical roles in cell-cell communication, tissue patterning, and angiogenesis during embryonic development and adult homeostasis. It is involved in vascular network formation, axon guidance, and tumor progression by regulating cell adhesion, migration, and signaling pathways. The Ab-330 clone recognizes a specific epitope within the extracellular domain of human EFNB2. enabling its detection in applications like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). Validated for specificity and sensitivity, this antibody is widely used in research to study EFNB2's function in developmental biology, cancer biology (particularly in tumor angiogenesis and metastasis), and neurological disorders. Its utility extends to both in vitro and in vivo models, providing insights into EFNB2-mediated signaling crosstalk and its therapeutic potential in diseases characterized by dysregulated Eph-ephrin interactions.