ADGRA2抗体,Rabbit Polyclonal ADGRA2 Antibody
  • ADGRA2抗体,Rabbit Polyclonal ADGRA2 Antibody
  • ADGRA2抗体,Rabbit Polyclonal ADGRA2 Antibody
  • ADGRA2抗体,Rabbit Polyclonal ADGRA2 Antibody

ADGRA2抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-12
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产品详情

中文名称:ADGRA2抗体英文名称:Rabbit Polyclonal ADGRA2 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 2678 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: ADGRA2
2025-05-12 ADGRA2抗体 Rabbit Polyclonal ADGRA2 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 2678 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesFLJ92027; H2A histone family, member C; H2A.1; H2A/c; H2A1; H2AFC; H2AFD; H2AFI; H2AFN; H2AFP; HIST1H2AG; HIST1H2AI; HIST1H2AK; HIST1H2AL; HIST1H2AM;;p-Histone H2A (S129)
WB Predicted band size14 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityYeast
ImmunogenA synthesized peptide derived from yeast Histone H2A around the phosphorylation site of S129
FormulationPurified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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       Western blot analysis of Phospho-Histone H2A (S129)  expression in Saccharomyces cerevisiae treated with Methyl methanesulfonate.    


           

参考文献

以下是关于ADGRA2抗体的虚构参考文献示例(实际文献需通过学术数据库检索):

1. **"ADGRA2 regulates neural progenitor migration during cortical development"**

- 作者:Smith J, et al.

- 摘要:本研究利用ADGRA2特异性抗体揭示了该蛋白在胚胎小鼠脑发育中调控神经前体细胞迁移的机制,抗体通过免疫荧光验证了其在皮层中的表达模式。

2. **"ADGRA2 as a novel biomarker in colorectal cancer progression"**

- 作者:Lee H, et al.

- 摘要:通过ADGRA2抗体的免疫组化分析,发现其在结直肠癌组织中高表达,并与患者预后不良相关,提示其可能作为潜在治疗靶点。

3. **"Characterization of a monoclonal antibody targeting ADGRA2 extracellular domain"**

- 作者:Wang Y, et al.

- 摘要:开发了一种针对ADGRA2胞外域的单克隆抗体,验证了其特异性及在流式细胞术和Western blot中的应用,为后续功能研究提供工具。

4. **"ADGRA2 modulates Wnt signaling in endothelial cell angiogenesis"**

- 作者:Garcia R, et al.

- 摘要:使用ADGRA2抗体阻断实验证明其通过调控Wnt/β-catenin通路影响血管内皮细胞迁移,提示其在血管生成中的潜在作用。

       

背景信息

The ADGRA2 (Adhesion G Protein-Coupled Receptor A2) antibody is a tool used to study the expression and function of ADGRA2. a member of the adhesion G protein-coupled receptor (GPCR) family. ADGRA2. also known as GPR124. is a transmembrane receptor characterized by a large extracellular N-terminus containing adhesion-related domains, such as leucine-rich repeats and immunoglobulin-like motifs. It plays critical roles in vascular and neural development, particularly in blood-brain barrier formation, angiogenesis, and central nervous system (CNS) patterning. ADGRA2 interacts with Wnt signaling pathways, acting as a co-receptor for Wnt7 ligands to regulate β-catenin-dependent signaling, essential for endothelial cell function and tissue homeostasis.

The ADGRA2 antibody is widely used in research to detect protein expression via techniques like Western blotting, immunohistochemistry, and immunofluorescence. It aids in elucidating ADGRA2's involvement in diseases, including cancer, where its dysregulation is linked to tumor angiogenesis and metastasis, and cerebrovascular disorders. Studies also explore its role in neuroinflammatory conditions and developmental anomalies. Validated for specificity and sensitivity, the antibody enables spatial and temporal analysis of ADGRA2 in biological samples, contributing to mechanistic insights and potential therapeutic targeting. Ongoing research continues to uncover its physiological and pathological significance across diverse tissues.

       
关键字: ADGRA2抗体;ADGRA2;ADGRA2 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
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