**Background of IGSF10 Antibodies**
The immunoglobulin superfamily member 10 (IGSF10) is a transmembrane protein belonging to the immunoglobulin superfamily, which plays roles in cell adhesion, signaling, and development. IGSF10 is notably involved in regulating cellular processes such as neuronal development, reproductive system function, and tissue morphogenesis. Studies suggest its association with congenital disorders, including hypogonadotropic hypogonadism and defects in brain connectivity.
IGSF10 antibodies are immunological tools designed to detect and study the expression, localization, and function of the IGSF10 protein. These antibodies are typically developed using immunogenic regions of IGSF10. such as its extracellular immunoglobulin domains or cytoplasmic regions, and are validated for applications like Western blotting, immunohistochemistry, and immunofluorescence.
Research utilizing IGSF10 antibodies has highlighted its expression in tissues like the brain, testes, and developing organs, supporting its role in neuroendocrine and reproductive biology. Dysregulation of IGSF10 has been linked to developmental anomalies, making these antibodies valuable for investigating molecular mechanisms in disease models. Commercial IGSF10 antibodies are often characterized for specificity and cross-reactivity across species, aiding translational research. Ongoing studies aim to clarify its interactions with signaling pathways and potential therapeutic targets.