ABCB6抗体,Rabbit Polyclonal ABCB6 Antibody
  • ABCB6抗体,Rabbit Polyclonal ABCB6 Antibody
  • ABCB6抗体,Rabbit Polyclonal ABCB6 Antibody
  • ABCB6抗体,Rabbit Polyclonal ABCB6 Antibody

ABCB6抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-13
QQ交谈 微信洽谈

产品详情

中文名称:ABCB6抗体英文名称:Rabbit Polyclonal ABCB6 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 3704 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: ABCB6
2025-05-13 ABCB6抗体 Rabbit Polyclonal ABCB6 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 3704 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesABC; LAN; PRP; umat; MTABC3
WB Predicted band size94 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human ABCB6
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Hela cell lysate, Primary antibody: P07728(ABCB6 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 90 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P07728(ABCB6 Antibody) at dilution 1/60. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P07728(ABCB6 Antibody) at dilution 1/60. (Original magnification: ×200)    


           

参考文献

以下是关于ABCB6抗体的3篇示例参考文献(内容为模拟概括,非真实文献):

1. **文献名称**:*ABCB6 Antibody Characterization in Drug-Resistant Cancer Cell Lines*

**作者**:Smith J, et al.

**摘要**:通过特异性ABCB6抗体验证其在多种癌症细胞系中的表达,发现ABCB6过表达与化疗药物外排及耐药性相关,提示其作为耐药标志物的潜力。

2. **文献名称**:*Subcellular Localization of ABCB6 Using Immunofluorescence Staining*

**作者**:Zhang L, et al.

**摘要**:利用ABCB6抗体进行亚细胞定位研究,证实其在线粒体和溶酶体膜上的双重分布,为研究其铁卟啉转运功能提供实验依据。

3. **文献名称**:*ABCB6 Gene Regulation and Protein Expression in Liver Disease*

**作者**:Tanaka K, et al.

**摘要**:通过Western blot和免疫组化分析ABCB6抗体,发现肝脏疾病中ABCB6表达上调,可能与血红素代谢异常及氧化应激反应相关。

4. **文献名称**:*Evaluation of Commercial ABCB6 Antibodies for Specificity and Sensitivity*

**作者**:Müller R, et al.

**摘要**:系统评估市售ABCB6抗体的性能,发现部分抗体存在非特异性结合,推荐使用C末端特异性抗体以提高实验可靠性。

(注:以上文献信息为基于领域知识的模拟生成,实际引用请以真实论文为准。)

       

背景信息

**Background of ABCB6 Antibody**

The ABCB6 antibody is a research tool targeting the ATP-binding cassette subfamily B member 6 (ABCB6) protein, a transporter within the ATP-binding cassette (ABC) superfamily. ABCB6 is implicated in multiple cellular processes, including porphyrin transport, heme biosynthesis, and mitochondrial function. It localizes to both the outer mitochondrial membrane and lysosomal membranes, suggesting roles in intracellular organelle communication and iron metabolism.

ABCB6 antibodies are widely used to study protein expression, localization, and function in various tissues and disease models. Dysregulation of ABCB6 has been linked to disorders such as iron-overload syndromes, chemotherapy resistance in cancers, and the rare genetic disorder dyschromatosis universalis hereditaria (DUH). Research utilizing these antibodies has revealed ABCB6's potential as a biomarker in cancer prognosis and its involvement in cellular detoxification pathways.

Antibody specificity is critical, as ABCB6 shares structural homology with other ABC transporters. Validation via knockout controls or siRNA-mediated silencing is often required. Commercial ABCB6 antibodies are typically developed in hosts like rabbits or mice, targeting specific epitopes (e.g., N-terminal or cytoplasmic domains). Applications include Western blotting, immunohistochemistry, and immunofluorescence, aiding in elucidating ABCB6's role in health and disease. Ongoing studies focus on its therapeutic potential in modulating drug resistance and metabolic disorders.

       
关键字: ABCB6抗体;ABCB6;ABCB6 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
询盘

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