ALDH3B1抗体,Rabbit Polyclonal ALDH3B1 Antibody
  • ALDH3B1抗体,Rabbit Polyclonal ALDH3B1 Antibody
  • ALDH3B1抗体,Rabbit Polyclonal ALDH3B1 Antibody
  • ALDH3B1抗体,Rabbit Polyclonal ALDH3B1 Antibody

ALDH3B1抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-13
QQ交谈 微信洽谈

产品详情

中文名称:ALDH3B1抗体英文名称:Rabbit Polyclonal ALDH3B1 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 3771 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: ALDH3B1
2025-05-13 ALDH3B1抗体 Rabbit Polyclonal ALDH3B1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 3771 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesALDH4; ALDH7
WB Predicted band size52 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human ALDH3B1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Human normal kidney tissue, Human liver tissue, human liver cancer tissue, Primary antibody: P07813(ALDH3B1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 45 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P07813(ALDH3B1 Antibody) at dilution 1/20. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P07813(ALDH3B1 Antibody) at dilution 1/20. (Original magnification: ×200)    


           

参考文献

以下是关于ALDH3B1抗体的3篇参考文献,按文献名称、作者和摘要内容概括列出:

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1. **"Aldehyde dehydrogenase 3B1 (ALDH3B1) promotes cellular resistance to oxidative stress in hepatocellular carcinoma"**

*Authors: Chen Y, et al.*

摘要:研究利用ALDH3B1特异性抗体,通过免疫组化分析发现ALDH3B1在肝癌组织中高表达,其通过清除氧化应激产物(如4-HNE)增强癌细胞存活能力,提示其作为肝癌治疗潜在靶点。

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2. **"ALDH3B1 as a prognostic biomarker in non-small cell lung cancer: Immunohistochemical analysis using a novel monoclonal antibody"**

*Authors: Smith RJ, et al.*

摘要:开发了一种新型ALDH3B1单克隆抗体,验证其在非小细胞肺癌(NSCLC)组织中的特异性。研究发现ALDH3B1高表达与患者不良预后相关,可能通过调控肿瘤干细胞特性促进转移。

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3. **"Differential expression of ALDH3B1 isoforms in breast cancer and their interaction with chemotherapeutic agents"**

*Authors: Gupta S, et al.*

摘要:通过Western blot和免疫荧光(使用ALDH3B1抗体)发现乳腺癌细胞中ALDH3B1存在两种亚型,其中一种亚型与化疗耐药性相关,机制涉及代谢解毒途径的激活。

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**备注**:以上文献名为示例,实际研究中建议通过PubMed或Web of Science搜索具体文献。若需全文,可使用DOI或联系作者获取。

       

背景信息

The aldehyde dehydrogenase 3 family member B1 (ALDH3B1) is an enzyme belonging to the ALDH superfamily, which plays a critical role in detoxifying endogenous and exogenous aldehydes by oxidizing them into carboxylic acids. ALDH3B1 is implicated in cellular defense against oxidative stress, metabolic regulation, and potential involvement in diseases such as cancer, neurodegenerative disorders, and alcohol-related pathologies. Its expression varies across tissues, with higher levels observed in the liver, kidneys, and respiratory tract.

ALDH3B1 antibodies are essential tools for detecting and quantifying ALDH3B1 protein expression in research applications like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). These antibodies aid in studying ALDH3B1's physiological roles, including its contribution to drug resistance in cancers, metabolic reprogramming, and response to oxidative damage. Commercially available ALDH3B1 antibodies are typically developed using immunogens derived from specific peptide sequences or recombinant proteins, ensuring specificity through validation in knockdown models or ALDH3B1-deficient cell lines.

Research utilizing ALDH3B1 antibodies has revealed its dual role as both a detoxifying enzyme and a potential biomarker. For instance, elevated ALDH3B1 levels are linked to poor prognosis in certain cancers, suggesting its utility in diagnostic or therapeutic strategies. However, functional studies remain limited, highlighting the need for further exploration of its mechanistic pathways. Reliable antibodies are thus critical for advancing understanding of ALDH3B1's multifunctional biology and its implications in disease pathogenesis.

       
关键字: ALDH3B1抗体;ALDH3B1;ALDH3B1 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
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