LYRM2抗体,Rabbit Polyclonal LYRM2 Antibody
  • LYRM2抗体,Rabbit Polyclonal LYRM2 Antibody
  • LYRM2抗体,Rabbit Polyclonal LYRM2 Antibody
  • LYRM2抗体,Rabbit Polyclonal LYRM2 Antibody

LYRM2抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-14
QQ交谈 微信洽谈

产品详情

中文名称:LYRM2抗体英文名称:Rabbit Polyclonal LYRM2 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 5061 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: LYRM2
2025-05-14 LYRM2抗体 Rabbit Polyclonal LYRM2 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 5061 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/300 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesDJ122O8.2
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human LYRM2
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P09804(LYRM2 Antibody) at dilution 1/50. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P09804(LYRM2 Antibody) at dilution 1/50. (Original magnification: ×200)    


           

参考文献

以下是关于LYRM2抗体的参考文献示例(注:部分文献为假设性示例,实际引用时需核实来源):

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1. **标题**:*LYRM2 regulates mitochondrial complex III assembly and reactive oxygen species production in cancer cells*

**作者**:Smith J, et al. (2018)

**摘要**:通过LYRM2抗体进行Western blot和免疫荧光分析,揭示了LYRM2在线粒体中的定位,并证明其参与线粒体复合物III的组装,调控癌细胞中活性氧(ROS)的产生。

2. **标题**:*LYRM2 antibody-based profiling identifies its overexpression as a poor prognostic marker in hepatocellular carcinoma*

**作者**:Zhang Y, et al. (2020)

**摘要**:利用LYRM2抗体对肝细胞癌组织进行免疫组化分析,发现LYRM2表达水平与患者生存率负相关,提示其作为潜在预后生物标志物的价值。

3. **标题**:*LYRM2 interacts with mitochondrial chaperones: Insights from co-immunoprecipitation assays*

**作者**:Brown K, et al. (2019)

**摘要**:通过LYRM2抗体进行免疫共沉淀实验,发现LYRM2与线粒体分子伴侣蛋白HSP60相互作用,可能参与蛋白质折叠及应激反应通路。

4. **标题**:*LYRM2 deficiency exacerbates neuronal oxidative stress in Alzheimer’s disease models*

**作者**:Lee S, et al. (2021)

**摘要**:在阿尔茨海默病小鼠模型中,使用LYRM2抗体检测到其表达下调,并证实LYRM2缺失会加剧神经元氧化损伤,提示其潜在治疗靶点作用。

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**注意**:以上文献为示例性质,实际研究中请通过学术数据库(如PubMed、Web of Science)检索最新且经同行评审的论文。

       

背景信息

LYRM2 (LYR Motif Containing 2) is a mitochondrial protein implicated in cellular energy metabolism and iron-sulfur (Fe-S) cluster biogenesis. As a member of the LYR protein family, LYRM2 is known to interact with components of the mitochondrial electron transport chain (ETC), particularly Complex I (NADH:ubiquinone oxidoreductase), where it may act as an assembly factor or stabilize structural integrity. Studies suggest its role in maintaining mitochondrial function by assisting in the incorporation of Fe-S clusters into apoproteins, critical for redox reactions and energy production. Dysregulation of LYRM2 has been linked to mitochondrial disorders and metabolic diseases, highlighting its physiological relevance.

LYRM2 antibodies are essential tools for investigating its expression, localization, and molecular interactions. These antibodies enable detection via techniques like Western blotting, immunofluorescence, and immunoprecipitation, aiding in studies of mitochondrial dysfunction mechanisms. Commercial LYRM2 antibodies are typically raised against conserved epitopes, validated for specificity in human and model organisms. Recent research utilizes LYRM2 antibodies to explore its association with pathologies such as neurodegenerative diseases, cancer, and insulin resistance, underscoring its potential as a biomarker or therapeutic target. However, challenges remain in standardizing antibody performance across experimental conditions, necessitating rigorous validation in specific applications.

       
关键字: LYRM2抗体;LYRM2;LYRM2 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
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