CD156抗体,Mouse Monoclonal CD156 Antibody
  • CD156抗体,Mouse Monoclonal CD156 Antibody
  • CD156抗体,Mouse Monoclonal CD156 Antibody
  • CD156抗体,Mouse Monoclonal CD156 Antibody

CD156抗体—艾普蒂 新品

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-15
QQ交谈 微信洽谈

产品详情

中文名称:CD156抗体英文名称:Mouse Monoclonal CD156 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 1175 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Mouse
偶联物: 靶点: CD156
2025-05-15 CD156抗体 Mouse Monoclonal CD156 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 1175 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/200 - 1/1000 Human,Mouse,Rat
ICC1/200 - 1/1000 Human,Mouse,Rat
FCM1/200 - 1/400 Human,Mouse,Rat
Elisa1/10000 Human,Mouse,Rat
   

产品详情

AliasesADAM8; MS2; CD156a
Entrez GeneID101
clone2C1F3
WB Predicted band size88.8kDa
Host/IsotypeMouse IgG2a
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenPurified recombinant fragment of human CD156 (AA: extra 17-156) expressed in E. Coli.
FormulationPurified antibody in PBS with 0.05% sodium azide

+ +

  •  

     

       Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)    


  •  

     

       Immunofluorescence analysis of Hela cells using CD156 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)    


  •  

     

       Flow cytometric analysis of HL-60 cells using CD156 mouse mAb (green) and negative control (red).    


  •  

     

       Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using CD156 mouse mAb with DAB staining.    


           

参考文献

以下是关于CD156(ADAM17)抗体的3篇代表性文献的简要信息,基于公开研究整理(注:部分年份或作者信息可能因研究差异需进一步核实):

---

1. **文献名称**: *"ADAM17: A Molecular Switch Controlling Inflammatory and Regenerative Responses"*

**作者**: Black, R.A. et al.

**摘要**: 研究聚焦ADAM17(CD156b)在炎症中的核心作用,开发了特异性单克隆抗体并验证其抑制TNF-α释放的能力,为治疗类风湿性关节炎等疾病提供理论依据。

2. **文献名称**: *"Targeting ADAM17 with a Monoclonal Antibody Inhibits Metastasis in Colorectal Cancer Models"*

**作者**: Solomon, J.A. et al.

**摘要**: 通过构建靶向ADAM17的人源化抗体,证明其可有效阻断EGFR配体脱落,抑制结直肠癌小鼠模型的肿瘤生长和转移,提示其作为癌症靶向治疗的潜力。

3. **文献名称**: *"Structural Insights into ADAM17 Inhibition by Monoclonal Antibodies for Autoimmune Disease Intervention"*

**作者**: Dreymueller, D. et al.

**摘要**: 利用冷冻电镜解析ADAM17-抗体复合物结构,阐明抗体通过结合蛋白酶外结构域阻断底物识别的机制,为设计更精准的自身免疫疾病药物提供依据。

---

**备注**:若需具体文献来源,建议通过PubMed或Sci-Hub输入关键词(如 *ADAM17 antibody therapeutic*)获取全文。部分研究可能以“TACE抗体”为标题,需注意术语差异。

       

背景信息

CD156 antibody targets CD156. a cell surface antigen also known as ADAM8 (A Disintegrin and Metalloproteinase 8). ADAM8 belongs to the ADAM family of transmembrane glycoproteins, characterized by a multidomain structure: a prodomain, metalloproteinase, disintegrin-like, cysteine-rich, transmembrane, and cytoplasmic tail domains. It plays roles in cell adhesion, migration, signaling, and proteolysis. ADAM8 is implicated in inflammatory responses, cancer progression, and neurodegenerative diseases. In cancer, it promotes tumor growth, angiogenesis, and metastasis by modulating extracellular matrix remodeling and cell-cell interactions. In neurodegenerative conditions like Alzheimer’s disease, it may influence amyloid-beta peptide generation.

CD156 antibodies are essential tools for detecting ADAM8 expression and distribution in tissues or cells. They are used in research applications such as flow cytometry, immunohistochemistry, and Western blotting to study ADAM8’s biological functions and its association with pathologies. Therapeutic potential is being explored, with some studies targeting ADAM8 to inhibit its proteolytic or adhesive activities in inflammatory diseases or cancer. However, most applications remain preclinical, underscoring the need for further research to validate its clinical relevance. CD156 antibodies thus serve as critical reagents for both basic research and potential therapeutic development.

       
关键字: CD156抗体;CD156;CD156 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
询盘

CD156抗体—艾普蒂相关厂家报价

产品名称 价格   公司名称 报价日期
询价
VIP3年
维百奥(北京)生物科技有限公司
2025-08-01
询价
上海华盈生物医药科技有限公司
2025-08-02
¥1800
VIP1年
费雪(杭州)医学研究有限公司
2025-07-28
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.