SPATA19抗体,Mouse Monoclonal SPATA19 Antibody
  • SPATA19抗体,Mouse Monoclonal SPATA19 Antibody
  • SPATA19抗体,Mouse Monoclonal SPATA19 Antibody
  • SPATA19抗体,Mouse Monoclonal SPATA19 Antibody

SPATA19抗体—艾普蒂 新品

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-16
QQ交谈 微信洽谈

产品详情

中文名称:SPATA19抗体英文名称:Mouse Monoclonal SPATA19 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 1508 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Mouse
偶联物: 靶点: SPATA19
2025-05-16 SPATA19抗体 Mouse Monoclonal SPATA19 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 1508 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/200 - 1/1000 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/10000 Human,Mouse,Rat
   

产品详情

AliasesCT132; SPAS1; spergen1
Entrez GeneID219938
clone5F5A10
WB Predicted band size19.1kDa
Host/IsotypeMouse IgG2b
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenPurified recombinant fragment of human SPATA19 (AA: 25-167) expressed in E. Coli.
FormulationPurified antibody in PBS with 0.05% sodium azide

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       Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)    


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       Immunohistochemical analysis of paraffin-embedded human testis tissues using SPATA19 mouse mAb with DAB staining.    


           

参考文献

以下是关于SPATA19抗体的3篇参考文献及其摘要概括(注:文献信息为模拟示例,实际研究中请以真实数据库为准):

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1. **文献名称**: *SPATA19 Antibody Production and Its Role in Human Spermatogenesis*

**作者**: Zhang L, et al.

**摘要**: 本研究首次报道了针对人SPATA19蛋白的多克隆抗体的制备与验证。通过免疫印迹和免疫组化实验,证实该抗体能特异性识别睾丸组织中的SPATA19蛋白,并揭示其在精子形成过程中的动态表达模式,提示SPATA19可能参与精子细胞分化调控。

2. **文献名称**: *Altered SPATA19 Expression in Infertile Males: An Immunohistochemical Study*

**作者**: Gupta R, et al.

**摘要**: 利用SPATA19特异性抗体对不育症患者的睾丸活检样本进行分析,发现SPATA19蛋白表达水平显著低于健康对照组,提示其表达异常可能与男性生精功能障碍相关,为临床诊断提供了潜在生物标志物。

3. **文献名称**: *SPATA19 Antibody-Based Detection of Oxidative Stress Response in Germ Cells*

**作者**: Tanaka K, et al.

**摘要**: 通过SPATA19抗体介导的免疫荧光技术,研究发现该蛋白在生殖细胞氧化应激反应中定位发生改变,进一步实验证实SPATA19可能通过调节线粒体功能参与细胞抗氧化机制。

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**说明**:以上文献为示例性质,实际研究中SPATA19相关抗体文献可能较少,建议通过PubMed或Web of Science以“SPATA19 AND (antibody OR immunohistochemistry)”为关键词检索最新成果。

       

背景信息

SPATA19 (spermatogenesis-associated protein 19) is a testis-specific gene implicated in male germ cell development. It encodes a protein predominantly expressed during spermatogenesis, particularly in spermatocytes and round spermatids. SPATA19 is thought to play a role in chromatin remodeling, meiotic progression, or acrosome formation, though its precise molecular mechanisms remain under investigation. Studies suggest its involvement in maintaining genomic stability during sperm maturation, potentially through interactions with other proteins in the seminiferous tubules.

Antibodies targeting SPATA19 are valuable tools for studying its expression pattern, subcellular localization, and functional roles in reproductive biology. These antibodies are typically produced using recombinant SPATA19 protein fragments or synthetic peptides as immunogens, often in rabbit or mouse hosts. They enable applications like Western blotting, immunohistochemistry, and immunofluorescence in testicular tissue or germ cell samples. Research utilizing SPATA19 antibodies has contributed to understanding male infertility mechanisms, as abnormal SPATA19 expression has been associated with spermatogenic defects. However, the protein's full physiological significance and clinical relevance in human reproductive disorders require further exploration. Commercial SPATA19 antibodies usually undergo validation in specific experimental contexts, though researchers are advised to verify cross-reactivity and specificity due to potential homology with other SPATA family proteins.

       
关键字: SPATA19抗体;SPATA19;SPATA19 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
询盘

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