NDUFAF2抗体,Rabbit Polyclonal NDUFAF2 Antibody
  • NDUFAF2抗体,Rabbit Polyclonal NDUFAF2 Antibody
  • NDUFAF2抗体,Rabbit Polyclonal NDUFAF2 Antibody
  • NDUFAF2抗体,Rabbit Polyclonal NDUFAF2 Antibody

NDUFAF2抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-16
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产品详情

中文名称:NDUFAF2抗体英文名称:Rabbit Polyclonal NDUFAF2 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 1986 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: NDUFAF2
2025-05-16 NDUFAF2抗体 Rabbit Polyclonal NDUFAF2 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 1986 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC咨询技术 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesMMTN; B17.2L; mimitin; NDUFA12L
WB Predicted band size20 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human NDUFAF2
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Raji cells, human liver cancer tissue, hela cells, Primary antibody: P01549(NDUFAF2 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds    


           

参考文献

以下是关于NDUFAF2抗体的3篇参考文献示例(注:以下为模拟内容,实际文献需通过学术数据库检索确认):

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1. **文献名称**: *NDUFAF2 functions as a mitochondrial complex I assembly factor and its deficiency causes Leigh syndrome*

**作者**: Ogilvie, I., et al.

**摘要**: 本研究通过Western blot和免疫荧光技术,利用NDUFAF2特异性抗体,揭示了其在复合物I组装中的关键作用。研究发现NDUFAF2突变导致线粒体功能异常,与早发性Leigh综合征相关。

2. **文献名称**: *Development of a monoclonal antibody against human NDUFAF2 for mitochondrial disease diagnostics*

**作者**: Chen, L., et al.

**摘要**: 报道了一种新型NDUFAF2单克隆抗体的开发,并通过免疫印迹和免疫组化验证其特异性。该抗体可用于线粒体病患者样本中NDUFAF2蛋白水平的检测,辅助临床诊断。

3. **文献名称**: *Tissue-specific expression profiling of NDUFAF2 in mammalian organs using immunohistochemistry*

**作者**: Sato, M., et al.

**摘要**: 利用NDUFAF2多克隆抗体对小鼠多种组织进行免疫组化分析,发现其在高能量需求器官(如心脏、肝脏)中高表达,提示其在维持线粒体能量代谢中的组织特异性功能。

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如需获取真实文献,建议在PubMed或Google Scholar中搜索关键词“NDUFAF2 antibody”、“NDUFAF2 immunohistochemistry”或结合疾病名称(如“mitochondrial complex I deficiency”)进行检索。

       

背景信息

NDUFAF2 (NADH:ubiquinone oxidoreductase complex assembly factor 2) is a mitochondrial protein critical for the assembly and stability of mitochondrial complex I, a key component of the electron transport chain (ETC) responsible for ATP production. This protein, also known as human complex I intermediate-associated protein 30 (hCIA30), facilitates the proper maturation of complex I subunits and coordinates their integration into the functional holoenzyme. Dysregulation of NDUFAF2 has been linked to mitochondrial disorders, particularly Leigh syndrome, a severe neurodegenerative condition characterized by impaired energy metabolism.

Antibodies targeting NDUFAF2 are essential tools for studying complex I biogenesis, mitochondrial dysfunction, and related pathologies. They enable detection of NDUFAF2 expression levels via Western blotting, immunofluorescence, or immunohistochemistry, aiding in the diagnosis of mitochondrial diseases and research into their molecular mechanisms. Additionally, these antibodies help investigate the protein's role in cellular processes like apoptosis, oxidative stress response, and metabolic adaptation. Recent studies also explore NDUFAF2's potential involvement in cancer progression and neurodegenerative diseases, as altered ETC function is increasingly recognized in these contexts. Validated antibodies with high specificity are crucial for distinguishing NDUFAF2 from homologous proteins and ensuring accurate experimental outcomes in both clinical and research settings.

       
关键字: NDUFAF2抗体;NDUFAF2;NDUFAF2 Antibody;

公司简介

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主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
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  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
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