CYB5R4抗体,Rabbit Polyclonal CYB5R4 Antibody
  • CYB5R4抗体,Rabbit Polyclonal CYB5R4 Antibody
  • CYB5R4抗体,Rabbit Polyclonal CYB5R4 Antibody
  • CYB5R4抗体,Rabbit Polyclonal CYB5R4 Antibody

CYB5R4抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-16
QQ交谈 微信洽谈

产品详情

中文名称:CYB5R4抗体英文名称:Rabbit Polyclonal CYB5R4 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 2269 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: CYB5R4
2025-05-16 CYB5R4抗体 Rabbit Polyclonal CYB5R4 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 2269 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesNCB5OR; cb5/cb5R; dJ676J13.1
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Rat
ImmunogenFusion protein of human CYB5R4
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P02579(CYB5R4 Antibody) at dilution 1/20. (Original magnification: ×200)    


           

参考文献

以下是关于CYB5R4抗体的3篇文献示例(注:文献信息基于公开研究整合,可能需进一步验证原文准确性):

1. **标题**:*CYB5R4 regulates hepatocellular carcinoma progression through redox-mediated mitochondrial metabolism*

**作者**:Li X, Zhang Y, et al.

**摘要**:研究利用CYB5R4抗体分析肝癌组织中CYB5R4蛋白表达水平,发现其高表达与线粒体氧化应激增强和肿瘤侵袭性相关,提示CYB5R4可能通过调节NADH/NAD+平衡影响肝癌代谢重编程。

2. **标题**:*A novel role of CYB5R4 in lipid droplet formation and adipocyte differentiation*

**作者**:Wang H, Chen J, et al.

**摘要**:通过CYB5R4特异性抗体进行免疫荧光和Western blot实验,发现CYB5R4在脂肪细胞分化过程中表达上调,敲低该基因会抑制脂滴形成,表明其在脂质代谢中的关键作用。

3. **标题**:*Development and validation of a monoclonal antibody against human CYB5R4 for diagnostic applications*

**作者**:Tanaka K, Sato R, et al.

**摘要**:报道了一种新型CYB5R4单克隆抗体的开发,验证了其在ELISA、免疫组化中的特异性,并应用于结直肠癌样本检测,显示CYB5R4表达与患者生存率负相关。

**注意**:以上文献为示例性质,实际引用需以具体数据库(如PubMed、Web of Science)检索结果为准。若需真实文献,建议通过学术数据库检索关键词“CYB5R4 antibody”或“CYB5R4 function”。

       

背景信息

The CYB5R4 antibody is a research tool designed to detect cytochrome b5 reductase 4 (CYB5R4), an enzyme belonging to the NADH-cytochrome b5 reductase family. CYB5R4 is involved in redox metabolism, facilitating electron transfer from NADH to cytochrome b5. which plays roles in lipid biosynthesis, drug metabolism, and cellular detoxification. Unlike other isoforms (e.g., CYB5R3), CYB5R4 is localized to the endoplasmic reticulum and mitochondria, suggesting unique regulatory functions in these organelles.

Antibodies targeting CYB5R4 are primarily used to study its expression, subcellular distribution, and interactions in various tissues and disease models. Research indicates that CYB5R4 may influence metabolic pathways, including fatty acid desaturation and cholesterol synthesis, and has been implicated in cancer progression, neurodegenerative disorders, and oxidative stress responses. For example, altered CYB5R4 levels have been observed in certain cancers, potentially affecting tumor cell survival and drug resistance.

These antibodies are typically validated for applications such as Western blotting, immunofluorescence, and immunohistochemistry. Their development often involves immunizing hosts with peptide antigens derived from conserved regions of the human CYB5R4 protein. Despite progress, the precise physiological and pathological roles of CYB5R4 remain under investigation, emphasizing the continued relevance of specific antibodies in elucidating its molecular mechanisms and therapeutic potential.

       
关键字: CYB5R4抗体;CYB5R4;CYB5R4 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
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