SNX30抗体,Rabbit Polyclonal SNX30 Antibody
  • SNX30抗体,Rabbit Polyclonal SNX30 Antibody
  • SNX30抗体,Rabbit Polyclonal SNX30 Antibody
  • SNX30抗体,Rabbit Polyclonal SNX30 Antibody

SNX30抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-18
QQ交谈 微信洽谈

产品详情

中文名称:SNX30抗体英文名称:Rabbit Polyclonal SNX30 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 2817 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: SNX30
2025-05-18 SNX30抗体 Rabbit Polyclonal SNX30 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 2817 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/20-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/1000-1/2000 Human,Mouse,Rat
   

产品详情

AliasesATG24A
WB Predicted band size50 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human SNX30
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human bladder carcinoma tissue, Primary antibody: P05346(SNX30 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P05346(SNX30 Antibody) at dilution 1/20. (Original magnification: ×200)    


           

参考文献

以下是关于SNX30抗体的示例参考文献(注:以下文献信息为示例性虚构内容,实际引用时请核实真实文献):

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1. **文献名称**:*"A Monoclonal Antibody Targeting SNX30 Reveals Its Role in Endosomal Sorting"*

**作者**:Zhang, L. et al.

**摘要**:本研究开发了一种特异性识别SNX30蛋白的单克隆抗体,验证了其在免疫印迹和免疫荧光中的应用。结果表明,SNX30通过其PX结构域与内体膜结合,调控EGFR等受体的分选过程。

2. **文献名称**:*"SNX30 Antibody-Based Profiling Identifies Dysregulation in Neurodegenerative Models"*

**作者**:Kim, S. & Patel, R.

**摘要**:利用兔源多克隆SNX30抗体,作者发现SNX30在阿尔茨海默病模型中表达显著下调,并通过共聚焦显微镜观察到其与APP蛋白的共定位,提示其可能参与淀粉样蛋白代谢通路。

3. **文献名称**:*"Development and Validation of a Polyclonal Antibody for SNX30 in Lipid Raft Studies"*

**作者**:Garcia, M. et al.

**摘要**:该文献报道了一种高亲和力SNX30多克隆抗体的制备,并通过蛋白质组学分析证实SNX30富集于脂筏微区,可能通过调控膜胆固醇稳态影响细胞迁移。

4. **文献名称**:*"SNX30 Knockout and Antibody-Based Rescue Experiments Highlight Its Immune Regulatory Function"*

**作者**:Wang, Q. et al.

**摘要**:通过CRISPR-Cas9构建SNX30敲除细胞系,结合外源抗体阻断实验,发现SNX30通过调节TLR4内吞途径影响NF-κB信号激活,提示其在先天免疫中的潜在作用。

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如需真实文献,建议在PubMed或Google Scholar中检索关键词(如"SNX30 antibody" + "sorting nexin"),并筛选涉及抗体开发、验证或功能研究的论文。

       

背景信息

SNX30 (Sorting Nexin 30) is a member of the sorting nexin family, a group of proteins involved in membrane trafficking, endosomal sorting, and cellular signaling. These proteins typically contain a Phox homology (PX) domain, which binds phosphoinositides to facilitate membrane association. SNX30 is distinguished by its unique structural features, including a C-terminal region that may mediate protein-protein interactions or regulate subcellular localization. It is implicated in retrograde transport from endosomes to the Golgi apparatus and interacts with components of the retromer complex, which is critical for recycling receptors and cargos. Studies suggest SNX30 may also influence autophagy and lysosomal function, though its precise mechanistic roles remain under investigation.

Antibodies targeting SNX30 are essential tools for studying its expression, localization, and function. They are widely used in techniques like Western blotting, immunofluorescence, and immunoprecipitation to explore SNX30's involvement in cellular processes and disease contexts. Dysregulation of sorting nexins has been linked to neurodegenerative disorders, cancer, and metabolic diseases, making SNX30 antibodies valuable for probing its potential contributions to these conditions. Recent research has focused on characterizing SNX30's tissue-specific expression patterns and its interplay with trafficking pathways, highlighting its emerging role in cellular homeostasis and pathology.

       
关键字: SNX30抗体;SNX30;SNX30 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
询盘

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