DMRTA2抗体,Rabbit Polyclonal DMRTA2 Antibody
  • DMRTA2抗体,Rabbit Polyclonal DMRTA2 Antibody
  • DMRTA2抗体,Rabbit Polyclonal DMRTA2 Antibody
  • DMRTA2抗体,Rabbit Polyclonal DMRTA2 Antibody

DMRTA2抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-18
QQ交谈 微信洽谈

产品详情

中文名称:DMRTA2抗体英文名称:Rabbit Polyclonal DMRTA2 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 3107 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: DMRTA2
2025-05-18 DMRTA2抗体 Rabbit Polyclonal DMRTA2 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 3107 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human DMRTA2
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P06388(DMRTA2 Antibody) at dilution 1/50. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P06388(DMRTA2 Antibody) at dilution 1/50. (Original magnification: ×200)    


           

参考文献

以下是关于DMRTA2抗体的参考文献示例(注:以下内容为模拟示例,实际文献需通过学术数据库查询):

1. **文献名称**:*Dmrta2 regulates neural progenitor development in the mammalian forebrain*

**作者**:Smith J, et al.

**摘要**:研究利用DMRTA2抗体通过免疫组化和Western blot技术,揭示Dmrta2在小鼠前脑神经祖细胞增殖与分化中的关键作用,并发现其与Foxg1信号通路的相互作用。

2. **文献名称**:*DMRTA2 expression in testicular development and germ cell differentiation*

**作者**:Lee S, et al.

**摘要**:通过DMRTA2抗体的免疫荧光分析,发现DMRTA2在雄性小鼠睾丸发育过程中特异性表达于生殖细胞前体,提示其参与精子形成调控。

3. **文献名称**:*Epigenetic regulation by DMRTA2 in cortical neuron migration*

**作者**:Garcia R, et al.

**摘要**:研究使用DMRTA2抗体进行染色质免疫沉淀(ChIP-seq),证明DMRTA2通过调控下游靶基因(如Neurod1)的表观遗传修饰影响皮层神经元迁移。

4. **文献名称**:*DMRTA2 as a potential biomarker in neuroblastoma: An immunohistochemical study*

**作者**:Chen H, et al.

**摘要**:基于DMRTA2抗体的免疫组化分析,发现DMRTA2在神经母细胞瘤中表达显著下调,提示其作为肿瘤抑制因子的潜在临床意义。

**建议**:实际文献可通过PubMed、Google Scholar等平台以关键词“DMRTA2 antibody”或“Dmrta2 function”检索,或参考抗体供应商(如Abcam、Sigma-Aldrich)的技术文档。

       

背景信息

DMRTA2 (Doublesex and Mab-3 Related Transcription Factor A2) is a member of the DMRT gene family, which encodes zinc finger-like transcription factors involved in developmental processes, particularly sex determination and differentiation. DMRTA2 is evolutionarily conserved and plays critical roles in embryonic development, including neurogenesis and cortical patterning. Studies suggest its involvement in regulating neural progenitor cell proliferation, differentiation, and regional identity in the developing brain. Dysregulation of DMRTA2 has been linked to neurodevelopmental disorders and certain cancers, such as neuroblastoma.

Antibodies targeting DMRTA2 are essential tools for investigating its expression, localization, and function. These antibodies are typically produced using immunogenic peptides or recombinant protein fragments specific to conserved regions of DMRTA2. They are widely used in techniques like Western blotting, immunohistochemistry, and immunofluorescence to detect endogenous DMRTA2 protein in tissues or cell lines. Validation often includes knockout/knockdown controls to confirm specificity. Commercially available DMRTA2 antibodies vary in host species (e.g., rabbit, mouse) and clonality (polyclonal/monoclonal), with applications spanning developmental biology, neuroscience, and cancer research. Recent studies have utilized these antibodies to explore DMRTA2's role in brain malformations and tumorigenesis, highlighting its potential as a therapeutic target or biomarker.

       
关键字: DMRTA2抗体;DMRTA2;DMRTA2 Antibody;

公司简介

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员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
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  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
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