HNRNPA1L2抗体,Rabbit Polyclonal HNRNPA1L2 Antibody
  • HNRNPA1L2抗体,Rabbit Polyclonal HNRNPA1L2 Antibody
  • HNRNPA1L2抗体,Rabbit Polyclonal HNRNPA1L2 Antibody
  • HNRNPA1L2抗体,Rabbit Polyclonal HNRNPA1L2 Antibody

HNRNPA1L2抗体—艾普蒂 新品

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-18
QQ交谈 微信洽谈

产品详情

中文名称:HNRNPA1L2抗体英文名称:Rabbit Polyclonal HNRNPA1L2 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 3216 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: HNRNPA1L2
2025-05-18 HNRNPA1L2抗体 Rabbit Polyclonal HNRNPA1L2 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 3216 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC咨询技术 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesATP1A1; Sodium/potassium-transporting ATPase subunit alpha-1; Na(+)/K(+) ATPase alpha-1 subunit; Sodium pump subunit alpha-1
Entrez GeneID24211
WB Predicted band sizeCalculated MW: 113 kDa; Observed MW: 113 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityRat
ImmunogenThe antiserum was produced against synthesized peptide derived from rat ATP1 alpha1/Na+K+ ATPase1 around the phosphorylation site of Ser23. AA range:15-64
FormulationPurified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.

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       Western blot analysis of Phospho-alpha 1 Sodium Potassium ATPase (Ser23) in rat lysates using Phospho-alpha 1 Sodium Potassium ATPase (Ser23) antibody.    


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       Western blot analysis of Phospho-alpha 1 Sodium Potassium ATPase (Ser23) in rat brain lysates using ATP1 alpha1/Na+K+ ATPase1 (Phospho-Ser23) antibody. The lane on the right is blocked with the Phospho- peptide.    


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       Immunofluorescence analysis of Phospho-alpha 1 Sodium Potassium ATPase (Ser23) in NIH/3T3 using ATP1 alpha1/Na+K+ ATPase1 (Phospho-Ser23) antibody. The picture on the right is blocked using the Phospho- peptide.    


           

参考文献

以下是基于现有文献的模拟示例,由于HNRNPA1L2研究较为小众,实际文献可能有限。建议通过PubMed或Google Scholar以关键词“HNRNPA1L2 antibody”进一步检索最新进展:

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1. **文献名称**: "HNRNPA1L2 as a novel biomarker in hepatocellular carcinoma: Expression analysis using a specific polyclonal antibody"

**作者**: Zhang Y, et al.

**摘要**: 本研究开发了一种针对HNRNPA1L2的多克隆抗体,并通过免疫组化和Western blot验证其在肝癌组织中的高表达,提示其作为潜在诊断标志物的可能性。

2. **文献名称**: "Role of HNRNPA1L2 in mRNA splicing regulation: Insights from antibody-mediated knockdown experiments"

**作者**: Lee S, Kim JH.

**摘要**: 利用特异性抗体阻断HNRNPA1L2的RNA结合功能,发现其调控多种前体mRNA的剪接过程,影响细胞周期相关基因表达。

3. **文献名称**: "Commercial antibody validation for HNRNPA1L2: A comparative study across multiple cancer cell lines"

**作者**: Smith R, et al.

**摘要**: 评估了市售HNRNPA1L2单克隆抗体的特异性,发现部分抗体存在交叉反应性,强调验证抗体在特定实验模型中的必要性。

4. **文献名称**: "HNRNPA1L2 aggregation in neurodegenerative diseases: Immunohistochemical detection with a novel antibody"

**作者**: Patel K, et al.

**摘要**: 开发了一种高灵敏度抗体用于检测HNRNPA1L2在阿尔茨海默病患者脑组织中的异常聚集,探讨其与tau蛋白病理的相关性。

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**注意**:上述内容为模拟生成,实际文献需通过学术数据库核实。若需具体文章,建议访问PubMed(https://pubmed.ncbi.nlm.nih.gov)并搜索“HNRNPA1L2 antibody”获取最新结果。

       

背景信息

The HNRNPA1L2 antibody is a tool used to study the heterogeneous nuclear ribonucleoprotein A1-like 2 (HNRNPA1L2), a member of the HNRNP family involved in RNA metabolism. HNRNPA1L2 shares structural homology with HNRNPA1. including RNA-binding domains critical for pre-mRNA processing, splicing, and transport. While its exact biological role remains under investigation, HNRNPA1L2 is hypothesized to regulate gene expression by interacting with RNA transcripts or participating in stress granule dynamics.

This antibody is primarily utilized in research applications such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to detect HNRNPA1L2 expression and localization in cells or tissues. Studies suggest potential links between HNRNPA1L2 dysregulation and diseases, including neurodegenerative disorders or cancers, where RNA processing errors are implicated. However, its clinical significance is less established compared to well-characterized HNRNP proteins like HNRNPA1 or HNRNPA2B1.

Commercial HNRNPA1L2 antibodies are typically validated for specificity, given the high sequence similarity among HNRNP family members. Researchers employ these reagents to explore its role in cellular stress responses, viral infection pathways, or as a biomarker in disease models. Further work is needed to clarify its mechanistic contributions and therapeutic relevance.

       
关键字: HNRNPA1L2抗体;HNRNPA1L2;HNRNPA1L2 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
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