PR 39 (porcine)/139637-11-9/抗菌肽PR 39(porcine)

Product Name：PR-39

CAS No.：139637-11-9

Synonyms.：抗菌肽PR 39(porcine)

Catalog No.：PYC-213

Description：PR-39 是富含脯氨酸和精氨酸的天然抗菌肽，是一种非竞争性，可逆和变构的蛋白酶体 (proteasome) 抑制剂多肽，其由39个氨基酸组成。PR-39可逆地结合到蛋白酶体的α7亚基上，并通过泛素-蛋白酶体途径阻断 NF-κB 抑制剂 IκBα 的降解。PR-39 刺激小鼠的血管生成，抑制炎症反应并显着减小心肌梗死面积。

PR-39 is a natural antimicrobial peptide rich in proline and arginine. It is a non competitive, reversible, and allosteric proteasome inhibitor peptide composed of 39 amino acids. PR-39 reversibly binds to the α 7 subunit of the proteasome and blocks the degradation of NF - κ B inhibitor I κ B α through the ubiquitin proteasome pathway. PR-39 stimulates angiogenesis in mice, inhibits inflammatory response, and significantly reduces myocardial infarction area.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

Sequence(1-letter code)	RRRPRPPYLPRPRPPPFFPPRLPPRIPPGFPPRFPPRFP-NH2
Sequence(3-letter code)	Arg-Arg-Arg-Pro-Arg-Pro-Pro-Tyr-Leu-Pro-Arg-Pro-Arg-Pro-Pro-Pro-Phe-Phe-Pro-Pro-Arg-Leu-Pro-Pro-Arg-Ile-Pro-Pro-Gly-Phe-Pro-Pro-Arg-Phe-Pro-Pro-Arg-Phe-Pro-NH2
Peptide Structure
Molecular Formula	C229H346N70O40
Molecular Weight	4719.74

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