SNAP47抗体,Rabbit Polyclonal SNAP47 Antibody
  • SNAP47抗体,Rabbit Polyclonal SNAP47 Antibody
  • SNAP47抗体,Rabbit Polyclonal SNAP47 Antibody
  • SNAP47抗体,Rabbit Polyclonal SNAP47 Antibody

SNAP47抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-19
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产品详情

中文名称:SNAP47抗体英文名称:Rabbit Polyclonal SNAP47 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 4367 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: SNAP47
2025-05-19 SNAP47抗体 Rabbit Polyclonal SNAP47 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 4367 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/200-1/400 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesSVAP1; HEL170; SNAP-47; C1orf142; ESFI5812; HEL-S-290
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFusion protein of human SNAP47
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P08790(SNAP47 Antibody) at dilution 1/200. (Original magnification: ×200)    


           

参考文献

以下是关于SNAP47抗体的3篇参考文献概述:

1. **"SNAP47 regulates cargo delivery via selective association with a subset of vesicle-associated membrane proteins"**

*作者:Zhang et al. (2018)*

摘要:研究揭示了SNAP47通过与特定VAMP蛋白(如VAMP7)的相互作用调控内体-溶酶体系统的膜融合过程,使用特异性抗体验证其在细胞内的定位及功能。

2. **"Distinct SNARE complexes mediating membrane fusion in different cellular compartments"**

*作者:Wang & Tang (2016)*

摘要:通过免疫沉淀和Western blot分析,发现SNAP47与Syntaxin6/VAMP4复合物结合,参与高尔基体到内体的运输,抗体实验证实其在不同细胞器中的分布差异。

3. **"SNAP47 interacts with ATG14 to modulate autophagosome-lysosome fusion"**

*作者:Chen et al. (2020)*

摘要:研究利用SNAP47抗体进行共定位及敲低实验,证明SNAP47通过与自噬相关蛋白ATG14结合,影响自噬体与溶酶体的融合效率。

       

背景信息

The SNAP47 antibody is a research tool designed to detect SNAP47 (Synaptosomal-associated protein 47), a member of the SNARE (soluble NSF attachment protein receptor) family involved in intracellular membrane fusion processes. SNAP47. encoded by the SNAP47 gene in humans, shares structural homology with other SNAP proteins like SNAP25 and SNAP29 but exhibits distinct localization and functional roles. It is broadly expressed across tissues and participates in diverse trafficking pathways, including endosomal sorting, autophagosome-lysosome fusion, and unconventional secretion. Unlike its homologs, SNAP47 localizes to both neuronal and non-neuronal compartments, suggesting versatility in membrane dynamics.

Researchers utilize SNAP47 antibodies primarily in techniques like Western blotting, immunofluorescence, and immunoprecipitation to study its expression, interaction partners, and subcellular distribution. These antibodies are critical for exploring SNAP47’s role in cellular homeostasis, neurodegenerative diseases (e.g., Alzheimer’s), and cancer, where disrupted membrane trafficking is implicated. Commercial SNAP47 antibodies are often validated for specificity against recombinant proteins or knockout cell lines to minimize cross-reactivity with other SNAREs. Challenges include distinguishing isoforms and detecting low-abundance endogenous SNAP47 in certain cell types. Recent studies highlight its involvement in LC3-associated phagocytosis and mTOR signaling, underscoring its emerging importance in cell biology and therapeutic targeting.

       
关键字: SNAP47抗体;SNAP47;SNAP47 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
询盘

SNAP47抗体—艾普蒂相关厂家报价

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