TALDO1抗体,Rabbit Polyclonal TALDO1 Antibody
  • TALDO1抗体,Rabbit Polyclonal TALDO1 Antibody
  • TALDO1抗体,Rabbit Polyclonal TALDO1 Antibody
  • TALDO1抗体,Rabbit Polyclonal TALDO1 Antibody

TALDO1抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-19
QQ交谈 微信洽谈

产品详情

中文名称:TALDO1抗体英文名称:Rabbit Polyclonal TALDO1 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 4431 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: TALDO1
2025-05-19 TALDO1抗体 Rabbit Polyclonal TALDO1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 4431 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB1/500-1/2000 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesTAL; TALH; TAL-H; TALDOR
WB Predicted band size38 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human TALDO1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-6: Mouse kidney tissue, Human kidney tissue, Mouse brain tissue, A431 cells, Human placenta tissue, Human fetal brain tissue, Primary antibody: P08898(TALDO1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P08898(TALDO1 Antibody) at dilution 1/30. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P08898(TALDO1 Antibody) at dilution 1/30. (Original magnification: ×200)    


           

参考文献

以下是基于TALDO1相关研究的模拟参考文献示例(仅供参考,具体文献需通过学术数据库核实):

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1. **文献名称**: *"TALDO1 Expression in Hepatocellular Carcinoma: A Prognostic Biomarker Study"*

**作者**: Li Y, et al.

**摘要**: 本研究通过免疫组化(IHC)和Western blot分析,发现TALDO1蛋白在肝癌组织中显著高表达,且与患者预后不良相关。使用兔源多克隆TALDO1抗体(ABC公司)验证了其作为潜在生物标志物的价值。

2. **文献名称**: *"Role of TALDO1 in Cellular Redox Homeostasis via the Pentose Phosphate Pathway"*

**作者**: Smith J, Patel R.

**摘要**: 通过CRISPR敲除细胞模型和TALDO1特异性抗体(货号#AB123. Sigma),证实TALDO1缺失导致NADPH/GSH水平下降,并增加氧化应激敏感性,表明其在维持细胞氧化还原平衡中的关键作用。

3. **文献名称**: *"Validation of a Novel Monoclonal Antibody for TALDO1 in Metabolic Disorders"*

**作者**: Garcia S, et al.

**摘要**: 报道了一种高特异性小鼠抗人TALDO1单克隆抗体的开发与验证(ELISA/WB/IHC),并应用于代谢疾病模型,发现TALDO1在肝脏和肾脏中的异常表达与果糖代谢紊乱相关。

4. **文献名称**: *"TALDO1 Knockdown and Antibody-Based Detection in Diabetic Nephropathy"*

**作者**: Kim H, et al.

**摘要**: 利用siRNA沉默TALDO1基因及兔多克隆抗体(Proteintech, 1:1000稀释)进行蛋白检测,证明TALDO1下调加剧糖尿病肾病模型中的炎症反应和纤维化进程。

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**建议**:实际文献需通过PubMed、Google Scholar等平台搜索关键词“TALDO1 antibody” “TALDO1 immunohistochemistry”等获取,并关注近5年研究以获最新进展。

       

背景信息

The TALDO1 antibody targets the transaldolase 1 protein, encoded by the TALDO1 gene in humans. Transaldolase 1 is a key enzyme in the pentose phosphate pathway (PPP), a metabolic route that generates NADPH and ribose-5-phosphate, essential for nucleotide synthesis and cellular redox balance. TALDO1 catalyzes the reversible transfer of a three-carbon ketol unit between sugar phosphates, linking the PPP to glycolysis. Dysregulation of TALDO1 has been implicated in metabolic disorders, cancer progression, and mitochondrial dysfunction.

TALDO1 antibodies are widely used in research to study the protein's expression, localization, and function in various tissues and disease models. They are critical tools for detecting TALDO1 via techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). Studies using these antibodies have revealed associations between TALDO1 deficiency and rare genetic disorders, such as transaldolase deficiency, characterized by liver dysfunction, developmental delays, and abnormal coagulation. In cancer biology, TALDO1 overexpression has been linked to tumor proliferation and metastasis, highlighting its potential as a therapeutic target.

Commercial TALDO1 antibodies are typically validated for specificity and sensitivity, often using knockout controls. Researchers rely on these reagents to explore metabolic adaptations in diseases, offering insights into PPP-driven mechanisms underlying cellular stress responses and pathological conditions.

       
关键字: TALDO1抗体;TALDO1;TALDO1 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
普通会员
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
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