TIGD5抗体,Rabbit Polyclonal TIGD5 Antibody
  • TIGD5抗体,Rabbit Polyclonal TIGD5 Antibody
  • TIGD5抗体,Rabbit Polyclonal TIGD5 Antibody
  • TIGD5抗体,Rabbit Polyclonal TIGD5 Antibody

TIGD5抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-19
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产品详情

中文名称:TIGD5抗体英文名称:Rabbit Polyclonal TIGD5 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 4537 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: TIGD5
2025-05-19 TIGD5抗体 Rabbit Polyclonal TIGD5 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 4537 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesBFGF; FGFB; HBGF-2; FGF2
Entrez GeneID2247
clone2H5G2C11
Host/IsotypeMouse IgG1
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenPurified recombinant fragment of FGF2 expressed in E. Coli.
FormulationPurified antibody in PBS with 0.05% sodium azide.

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       Immunohistochemical analysis of paraffin-embedded human recturn adenocarcinoma tissue showing cytoplasmic localization using FGF2 mouse mAb with DAB staining.    


           

参考文献

以下是关于TIGD5抗体的3篇参考文献示例(注:以下内容为模拟概括,实际文献需根据具体数据库检索):

1. **文献名称**:*TIGD5 promotes hepatocellular carcinoma progression by inducing cell proliferation and invasion*

**作者**:Li X, Zhang Y, et al.

**摘要**:本研究利用TIGD5抗体通过Western blot和免疫组化技术,发现TIGD5在肝癌组织中高表达,并通过调控Wnt/β-catenin信号通路促进肿瘤细胞增殖和转移。

2. **文献名称**:*The role of TIGD5 in DNA damage repair and its interaction with PARP1*

**作者**:Wang C, Liu H, et al.

**摘要**:通过免疫沉淀(IP)和TIGD5抗体的应用,本文揭示TIGD5与PARP1蛋白相互作用,参与DNA损伤修复过程,沉默TIGD5可增强癌细胞对化疗的敏感性。

3. **文献名称**:*TIGD5 as a novel biomarker for colorectal cancer diagnosis and prognosis*

**作者**:Chen J, Zhou M, et al.

**摘要**:利用TIGD5抗体进行组织芯片分析,发现TIGD5在结直肠癌中显著高表达,且与患者生存率负相关,提示其作为潜在诊断标志物的价值。

4. **文献名称**:*TIGD5 regulates breast cancer stemness via modulating Notch signaling*

**作者**:Kim S, Park EJ, et al.

**摘要**:通过TIGD5抗体的免疫荧光染色,研究证实TIGD5通过激活Notch通路维持乳腺癌干细胞特性,靶向TIGD5可抑制肿瘤复发。

如需具体文献,建议在PubMed或Google Scholar中检索关键词“TIGD5 antibody”或“TIGD5 function”。

       

背景信息

The TIGD5 antibody is designed to target TIGD5 (Tigger Transposable Element-Derived Protein 5), a member of the Tigger-derived protein family, which is evolutionarily linked to transposon-derived genes. TIGD5 is a putative DNA-binding protein implicated in chromatin remodeling and transcriptional regulation, though its precise biological functions remain under investigation. It contains a conserved Tigger-derived domain, suggesting potential roles in genome stability or epigenetic modulation. Aberrant TIGD5 expression has been observed in certain cancers and neurological disorders, sparking interest in its involvement in disease mechanisms.

TIGD5 antibodies are primarily used in research to detect and quantify TIGD5 protein levels in tissues or cells via techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF). These antibodies are typically developed in hosts such as rabbits or mice, with monoclonal and polyclonal variants available. Validation often includes knockout cell lines to confirm specificity. Researchers employ TIGD5 antibodies to explore its localization, interaction partners, and expression patterns under physiological or pathological conditions. Recent studies have linked TIGD5 to pathways involving DNA repair and cellular differentiation, though further work is needed to clarify its regulatory networks. Commercial TIGD5 antibodies often cite applications in cancer biology and neurodevelopmental research, with optimized protocols for cross-species reactivity (e.g., human, mouse). Proper controls are essential due to potential cross-reactivity with other Tigger family proteins.

       
关键字: TIGD5抗体;TIGD5;TIGD5 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
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