PSMF1抗体,Rabbit Polyclonal PSMF1 Antibody
  • PSMF1抗体,Rabbit Polyclonal PSMF1 Antibody
  • PSMF1抗体,Rabbit Polyclonal PSMF1 Antibody
  • PSMF1抗体,Rabbit Polyclonal PSMF1 Antibody

PSMF1抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-19
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产品详情

中文名称:PSMF1抗体英文名称:Rabbit Polyclonal PSMF1 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 4585 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: PSMF1
2025-05-19 PSMF1抗体 Rabbit Polyclonal PSMF1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 4585 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesPI31
WB Predicted band size30 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFull length fusion protein
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: HEPG2 and Hela cell, Primary antibody: P09100(PSMF1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P09100(PSMF1 Antibody) at dilution 1/30. (Original magnification: ×200)    


           

参考文献

以下是关于PSMF1抗体的参考文献示例(注:以下内容为虚构示例,建议通过学术数据库检索真实文献):

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1. **文献名称**:*"PSMF1 modulates proteasome activity in cancer cells: Insights from antibody-based functional studies"*

**作者**:Chen L, et al.

**摘要**:该研究利用抗PSMF1抗体进行免疫印迹和免疫荧光实验,发现PSMF1通过抑制蛋白酶体活性延缓结肠癌细胞增殖,提示其作为潜在治疗靶点。

2. **文献名称**:*"Development of a high-specificity monoclonal antibody against PSMF1 for neurodegenerative disease research"*

**作者**:Martinez R, et al.

**摘要**:报道了一种新型单克隆抗体的开发与验证,证实其可特异性识别小鼠和人类脑组织中的PSMF1.并用于研究阿尔茨海默病模型中的蛋白异常聚集。

3. **文献名称**:*"PSMF1 expression profiling in hepatocellular carcinoma using a novel immunohistochemical antibody"*

**作者**:Wang X, et al.

**摘要**:通过新型抗PSMF1抗体进行免疫组化分析,发现PSMF1在肝癌组织中显著低表达,且与患者预后不良相关,提示其作为诊断标志物的潜力。

4. **文献名称**:*"PSMF1 regulates oxidative stress response via proteasome inhibition: Evidence from siRNA and antibody-mediated knockdown"*

**作者**:Kim S, et al.

**摘要**:结合siRNA和抗PSMF1抗体实验,证明PSMF1通过抑制蛋白酶体活性增强细胞对氧化应激的敏感性,揭示了其在氧化损伤中的调控机制。

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**建议**:如需真实文献,请通过PubMed或Google Scholar搜索关键词“PSMF1 antibody”或“PSMF1 proteasome inhibitor”,并筛选涉及抗体应用的研究。

       

背景信息

The PSMF1 (Proteasome Inhibitor 31 kDa Subunit Family Member 1) antibody is a tool used to study the PSMF1 protein, a regulator of proteasome activity. PSMF1. also known as PI31. binds to the 26S proteasome and modulates its function, influencing protein degradation pathways critical for cellular homeostasis. This protein is implicated in controlling proteasome assembly, substrate processing, and crosstalk between proteasomes and autophagy. Dysregulation of PSMF1 is linked to neurodegenerative diseases, cancer, and immune disorders, making it a focus in pathophysiological research.

PSMF1 antibodies are typically raised in rabbits or mice using recombinant protein fragments or synthetic peptides as immunogens. They are validated for applications like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to detect endogenous PSMF1 in human, mouse, or rat tissues. Commercial antibodies often include epitope specificity data and are used to explore PSMF1’s expression patterns, interactions (e.g., with proteasome subunits or autophagy-related proteins), and roles in stress responses or apoptosis. Researchers also employ these antibodies to investigate PSMF1’s dual role as both a proteasome inhibitor and activator under varying cellular conditions. Quality validation typically involves knockout controls or siRNA-mediated silencing to confirm signal specificity. Studies using PSMF1 antibodies have advanced understanding of its involvement in diseases like Alzheimer’s, multiple myeloma, and inflammation.

       
关键字: PSMF1抗体;PSMF1;PSMF1 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 2年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
询盘

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