Product Name：RLQN15
CAS No.：N/A
Synonyms：促愈合剂多肽RLQN15
Catalog No.：220P004
Brand：Typeptide Biotech（肽研生物）
Description：RL-QN15是由15个氨基酸组成的多肽，序列中含有一对二硫键，RL-QN15能加速小鼠的伤口愈合。对RL-QN15潜在机制的探讨表明，RL-QN15激活MAPK和Smad信号通路，并选择性地调节巨噬细胞分泌细胞因子。这引发了皮肤细胞的增殖和迁移以及伤口中TGF-β1和TGF- β3的动态调节，并且可以加速再上皮化和肉芽组织形成，从而促进皮肤再生。此外，RL-QN15针对慢性伤口、皮肤纤维化和口腔溃疡也显示出治疗效果。在这项研究中鉴定的新肽(R1-QN15)可以作为开发新促愈合剂的候选物。
RL-QN15 is a peptide composed of 15 amino acids, containing a pair of disulfide bonds in its sequence. RL-QN15 can accelerate wound healing in mice. The exploration of the potential mechanism of RL-QN15 suggests that it activates the MAPK and Smad signaling pathways and selectively regulates macrophage cytokine secretion. This triggers the proliferation and migration of skin cells, as well as the dynamic regulation of TGF - β 1 and TGF - β 3 in wounds, and can accelerate re epithelialization and granulation tissue formation, thereby promoting skin regeneration. In addition, RL-QN15 has also shown therapeutic effects on chronic wounds, skin fibrosis, and oral ulcers. The newly identified peptide (R1-QN15) in this study can serve as a candidate for developing new healing promoting agents.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | QNSYADLWCQFHYMC(Disulfide bridge: Cys9-Cys15) |
Sequence(3-letter code) | H-Gln-Asn-Ser-Tyr-Ala-Asp-Leu-Trp-Cys-Gln-Phe-His-Tyr-Met-Cys-OH(Disulfidebridge:Cys9-Cys15) |
Peptide Structure | 
|
Molecular Formula | C85H111N21O24S3 |
Molecular Weight | 1907.11 |
订购联系方式：
南京肽研生物生物科技有限公司
手机号：19961912513(微信同号)
QQ: 2178255659
邮箱：sales@typeptide.com
联系人：顾经理
申明：本产品仅供科研使用。
关键字： 促愈合剂多肽RLQN15;RLQN15;促愈合剂多肽;多肽;多肽工厂;
肽研生物坐落于国家级新区南京江北新区新材料产业园，是一家专业从事多肽产 品的研发、生产和销售以及多肽技术转让的高新技术企业。公司秉持“诚信、严 谨、务实”的匠人精神，持续投入研发，不断创新，致力于为科研工作者提供丰 富全面的多肽修饰类型和优质的产品。