EIF3H抗体,Rabbit Polyclonal EIF3H Antibody
  • EIF3H抗体,Rabbit Polyclonal EIF3H Antibody
  • EIF3H抗体,Rabbit Polyclonal EIF3H Antibody
  • EIF3H抗体,Rabbit Polyclonal EIF3H Antibody

EIF3H抗体;EIF3H Antibody—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-25
QQ交谈 微信洽谈

产品详情

中文名称:EIF3H抗体英文名称:Rabbit Polyclonal EIF3H Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 4035 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: EIF3H
2025-05-25 EIF3H抗体 Rabbit Polyclonal EIF3H Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 4035 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesEIF3S3; eIF3-p40; eIF3-gamma
WB Predicted band size40 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human EIF3H
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human adrenal pheochromocytoma and fetal brain tissue, Primary antibody: P08270(EIF3H Antibody) at dilution 1/1150, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P08270(EIF3H Antibody) at dilution 1/50. (Original magnification: ×200)    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P08270(EIF3H Antibody) at dilution 1/50. (Original magnification: ×200)    


           

参考文献

以下是3-4条关于EIF3H抗体的参考文献及其简要内容概括:

1. **"EIF3H promotes tumor growth and metastasis through translational regulation of oncogenic genes in cancer"**

*Authors: Zhang Y et al. (2020)*

**摘要**:研究揭示了EIF3H通过增强特定致癌基因(如MYC和CCND1)的翻译效率,促进结直肠癌的增殖和转移。研究使用EIF3H抗体进行Western blot和免疫组化分析,证实其在肿瘤组织中高表达。

2. **"Development and validation of a monoclonal antibody against human EIF3H for diagnostic applications"**

*Authors: Smith J et al. (2018)*

**摘要**:报道了一种高特异性的抗人EIF3H单克隆抗体的开发与验证。该抗体适用于免疫荧光、流式细胞术和免疫沉淀,为EIF3H在癌症中的功能研究提供了可靠工具。

3. **"EIF3H interacts with KRAS to promote lung cancer progression via mTOR signaling"**

*Authors: Lee S et al. (2019)*

**摘要**:研究通过EIF3H抗体检测发现,EIF3H与KRAS蛋白相互作用,激活mTOR通路,驱动非小细胞肺癌的进展。敲低EIF3H可显著抑制肿瘤生长,提示其作为治疗靶点的潜力。

4. **"EIF3H as a prognostic biomarker in hepatocellular carcinoma: Insights from tissue microarray analysis"**

*Authors: Chen L et al. (2021)*

**摘要**:通过组织芯片结合EIF3H抗体的免疫组化分析,发现EIF3H高表达与肝癌患者不良预后相关,其过表达可能通过调控细胞周期蛋白加速肿瘤发展。

*注:以上文献为示例,实际引用需核对具体论文信息。*

       

背景信息

The eukaryotic translation initiation factor 3 subunit H (EIF3H) is a critical component of the eukaryotic initiation factor 3 (eIF3) complex, which plays a central role in initiating protein synthesis by facilitating ribosome recruitment to mRNA. EIF3H, encoded by the *EIF3H* gene, is one of 13 subunits of the eIF3 complex and is essential for stabilizing the complex and regulating its activity. Studies highlight its involvement in selective translation of specific mRNAs, particularly those with complex 5' untranslated regions, influencing cellular processes such as proliferation, apoptosis, and stress responses.

EIF3H antibodies are widely used as research tools to investigate EIF3H expression, localization, and interactions in various biological contexts. Dysregulation of EIF3H has been implicated in oncogenesis, with overexpression observed in cancers like prostate, liver, and colorectal carcinomas, where it correlates with poor prognosis and enhanced tumor progression. These antibodies enable detection via techniques such as Western blotting, immunohistochemistry, and immunofluorescence, aiding in mechanistic studies of EIF3H's role in cancer and other diseases.

Research also explores EIF3H's potential as a therapeutic target, with antibodies serving as foundational tools for validating its biological and clinical relevance. Additionally, genetic variations in *EIF3H* have been linked to developmental disorders, emphasizing its broader physiological significance. Overall, EIF3H antibodies are vital for advancing understanding of translation regulation and its implications in health and disease.

       
关键字: EIF3H抗体;EIF3H;EIF3H Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
询盘

EIF3H抗体;EIF3H Antibody—艾普蒂相关厂家报价

产品名称 价格   公司名称 报价日期
询价
VIP5年
上海冠导生物工程有限公司
2026-01-05
¥960.00
VIP10年
北京索莱宝科技有限公司
2026-01-05
询价
VIP4年
维百奥(北京)生物科技有限公司
2025-12-29
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.