ZNF300抗体,Rabbit Polyclonal ZNF300 Antibody
  • ZNF300抗体,Rabbit Polyclonal ZNF300 Antibody
  • ZNF300抗体,Rabbit Polyclonal ZNF300 Antibody
  • ZNF300抗体,Rabbit Polyclonal ZNF300 Antibody

ZNF300抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-20
QQ交谈 微信洽谈

产品详情

中文名称:ZNF300抗体英文名称:Rabbit Polyclonal ZNF300 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 4679 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: ZNF300
2025-05-20 ZNF300抗体 Rabbit Polyclonal ZNF300 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 4679 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFusion protein of human ZNF300
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P09238(ZNF300 Antibody) at dilution 1/30. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P09238(ZNF300 Antibody) at dilution 1/30. (Original magnification: ×200)    


           

参考文献

以下是3篇关于ZNF300抗体的代表性文献示例(注:以下内容为示例性虚构,实际文献需通过学术数据库检索确认):

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1. **文献名称**: "ZNF300 regulates macrophage polarization via antibody-mediated TLR4 signaling inhibition"

**作者**: Li X, Zhang Y, et al.

**摘要**: 本研究利用抗ZNF300抗体探究该蛋白在巨噬细胞极化中的作用,发现ZNF300通过抑制TLR4信号通路调控炎症反应,抗体阻断实验证实其潜在免疫治疗价值。

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2. **文献名称**: "Development of a novel monoclonal antibody specific to human ZNF300 for cancer biomarker detection"

**作者**: Wang H, Chen J, et al.

**摘要**: 报道一种高特异性抗ZNF300单克隆抗体的开发,通过免疫组化验证其在乳腺癌组织中的高表达,提示ZNF300可能作为肿瘤诊断标志物。

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3. **文献名称**: "ZNF300 interacts with p53: Antibody-based co-immunoprecipitation analysis in gastric cancer cells"

**作者**: Tanaka K, et al.

**摘要**: 利用抗ZNF300抗体进行免疫共沉淀实验,首次揭示ZNF300与p53蛋白的相互作用,并证明其在胃癌细胞凋亡调控中的协同机制。

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如需真实文献,建议在PubMed/Google Scholar检索关键词"ZNF300 antibody"或"ZNF300 immunohistochemistry",并筛选近5年应用性研究。

       

背景信息

The ZNF300 antibody is a research tool designed to target the ZNF300 protein, a member of the zinc finger protein (ZFP) family. Zinc finger proteins are characterized by conserved cysteine and histidine residues that form structural motifs critical for DNA or RNA binding, enabling roles in transcriptional regulation, chromatin remodeling, and cellular differentiation. ZNF300. located on human chromosome 19. contains a KRAB (Krüppel-associated box) domain, a repression module that recruits chromatin-modifying complexes to regulate gene expression. Studies suggest ZNF300 may participate in immune responses, apoptosis, and cancer progression, though its precise biological functions remain under investigation.

Antibodies against ZNF300 are primarily used in molecular and cellular biology to detect endogenous ZNF300 protein expression via techniques like Western blotting, immunofluorescence, or immunohistochemistry. These antibodies are typically raised in hosts such as rabbits or mice, with validation steps including knockout/knockdown controls to confirm specificity. Commercially available ZNF300 antibodies aid in exploring its expression patterns in tissues or disease models, particularly in cancer research, where ZNF300 has been implicated as a potential oncogene in certain malignancies. For example, elevated ZNF300 levels correlate with tumor progression and poor prognosis in some studies, highlighting its potential as a therapeutic target or biomarker. However, further research is needed to fully elucidate its mechanisms and clinical relevance.

       
关键字: ZNF300抗体;ZNF300;ZNF300 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
普通会员
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
询盘

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