The ZNF512 antibody is a crucial tool for studying the zinc finger protein 512 (ZNF512), a member of the zinc finger protein family implicated in transcriptional regulation and cellular stress responses. ZNF512. also known as HIVEP3. contains multiple C2H2-type zinc finger domains, which enable its interaction with DNA or RNA to modulate gene expression. Research suggests ZNF512 plays roles in diverse biological processes, including cell proliferation, differentiation, and apoptosis. It has been linked to cancer progression (e.g., glioma, gastric cancer) and neurodegenerative diseases, potentially acting as a tumor suppressor or oncogene depending on context.
Studies highlight its involvement in oxidative stress pathways, where ZNF512 may regulate antioxidant enzymes like SOD2. offering protection against cellular damage. The ZNF512 antibody is widely used in techniques such as Western blotting (WB), immunohistochemistry (IHC), and immunofluorescence (IF) to detect protein expression levels, localization, and interactions in tissues or cell lines. Its specificity and validation (e.g., knockout validation) are critical for ensuring reliable results in both basic research and clinical studies.
As dysregulation of ZNF512 is increasingly associated with disease mechanisms, this antibody serves as a vital reagent for unraveling its molecular functions and therapeutic potential. Ongoing research aims to clarify its signaling networks and explore its utility as a biomarker or therapeutic target in precision medicine.