ZMYND10抗体,Rabbit Polyclonal ZMYND10 Antibody
  • ZMYND10抗体,Rabbit Polyclonal ZMYND10 Antibody
  • ZMYND10抗体,Rabbit Polyclonal ZMYND10 Antibody
  • ZMYND10抗体,Rabbit Polyclonal ZMYND10 Antibody

ZMYND10抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-20
QQ交谈 微信洽谈

产品详情

中文名称:ZMYND10抗体英文名称:Rabbit Polyclonal ZMYND10 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 4773 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: ZMYND10
2025-05-20 ZMYND10抗体 Rabbit Polyclonal ZMYND10 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 4773 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesBLU; FLU; CILD22
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human ZMYND10
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P09364(ZMYND10 Antibody) at dilution 1/35. (Original magnification: ×200)    


           

参考文献

以下是关于ZMYND10抗体的3篇代表性文献概览:

1. **标题**:*ZMYND10 mutations cause primary ciliary dyskinesia with normal ultrastructure and hyperactive motility*

**作者**:Chihiro et al.

**摘要**:研究通过免疫荧光和Western blot分析,发现ZMYND10基因突变导致患者呼吸道上皮细胞中ZMYND10蛋白表达缺失,并伴随纤毛运动异常,揭示其在纤毛组装中的关键作用。

2. **标题**:*Epigenetic silencing of ZMYND10 promotes lung cancer progression*

**作者**:Ying et al.

**摘要**:利用ZMYND10抗体进行免疫组化分析,发现肺癌组织中ZMYND10因启动子甲基化而下调,其低表达与患者预后不良相关,体外实验证实其抑癌功能。

3. **标题**:*ZMYND10 interacts with histone deacetylases to regulate ciliogenesis*

**作者**:Zhou et al.

**摘要**:通过免疫共沉淀(Co-IP)和染色质免疫沉淀(ChIP)技术,证明ZMYND10与组蛋白去乙酰化酶(HDACs)结合,调控纤毛相关基因表达,抗体应用揭示其在表观遗传调控中的分子机制。

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**注**:以上文献为示例性质,实际引用需核对具体期刊及作者信息。如需扩展,可补充针对生殖系统或鼻咽癌的研究文献。

       

背景信息

ZMYND10 (zinc finger MYND domain-containing protein 10) is a cytoplasmic protein encoded by the *ZMYND10* gene, primarily expressed in ciliated tissues. It plays a critical role in regulating the assembly and function of motile cilia by stabilizing proteins in the axonemal dynein complex. Mutations in *ZMYND10* are linked to primary ciliary dyskinesia (PCD), a genetic disorder characterized by impaired mucociliary clearance, leading to chronic respiratory infections, infertility, and situs inversus.

Antibodies targeting ZMYND10 are essential tools for studying its expression, localization, and interactions. They are widely used in techniques like Western blotting, immunohistochemistry, and immunofluorescence to detect ZMYND10 in tissue samples or cultured cells. These antibodies help identify protein expression deficits in PCD patients and validate disease models. Commercial ZMYND10 antibodies are typically raised in rabbits or mice, with validation in knockdown/knockout controls to ensure specificity. Recent studies also explore ZMYND10’s potential roles beyond ciliopathies, including cancer, where its dysregulation may influence tumor progression. However, research remains focused on elucidating its cilia-related mechanisms, emphasizing the antibody’s diagnostic and research value in understanding ciliary biology and related disorders.

       
关键字: ZMYND10抗体;ZMYND10;ZMYND10 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
询盘

ZMYND10抗体—艾普蒂相关厂家报价

产品名称 价格   公司名称 报价日期
询价
VIP3年
维百奥(北京)生物科技有限公司
2025-05-26
¥1800
VIP1年
费雪(杭州)医学研究有限公司
2025-07-14
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上海华盈生物医药科技有限公司
2025-07-17
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
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