The CGREF1 (Cell Growth and Repair-Enhancing Factor 1) antibody is a research tool designed to detect and study the CGREF1 protein, which is implicated in cellular growth, tissue repair, and regeneration processes. CGREF1. also known as CGRF1. is a secreted protein encoded by the CGREF1 gene, primarily expressed in the brain, kidneys, and other tissues. It plays a role in modulating cell proliferation, differentiation, and survival, particularly in neural and epithelial cells. Studies suggest its involvement in neuroprotection, wound healing, and cancer progression, where dysregulated expression may influence tumorigenesis or tissue repair efficiency.
The CGREF1 antibody, typically developed in rabbit or mouse models, enables researchers to investigate protein localization, expression levels, and interaction partners via techniques like Western blotting, immunohistochemistry, and immunofluorescence. Its applications extend to exploring CGREF1's functional mechanisms in disease models, such as neurodegenerative disorders, renal injury, or cancers. Validation data, including knockout controls and specificity assays, are critical to ensure reliable detection. Commercial availability and custom production options facilitate its use in both basic and translational research, aiding the development of therapeutic strategies targeting CGREF1-related pathways.