ARL4D抗体,Rabbit Polyclonal ARL4D Antibody
  • ARL4D抗体,Rabbit Polyclonal ARL4D Antibody
  • ARL4D抗体,Rabbit Polyclonal ARL4D Antibody
  • ARL4D抗体,Rabbit Polyclonal ARL4D Antibody

ARL4D抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-20
QQ交谈 微信洽谈

产品详情

中文名称:ARL4D抗体英文名称:Rabbit Polyclonal ARL4D Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 5242 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: ARL4D
2025-05-20 ARL4D抗体 Rabbit Polyclonal ARL4D Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 5242 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/300 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesARL6; ARF4L
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human ARL4D
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P10044(ARL4D Antibody) at dilution 1/50. (Original magnification: ×200)    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P10044(ARL4D Antibody) at dilution 1/50. (Original magnification: ×200)    


           

参考文献

以下是关于ARL4D抗体的3篇参考文献,按文献名称、作者和摘要内容概括整理:

---

1. **文献名称**: *ARL4D regulates cancer metastasis and stemness via Wnt/β-catenin signaling in colorectal cancer*

**作者**: Li X, Zhang Y, et al.

**摘要**: 该研究利用ARL4D特异性抗体,通过免疫组化和Western blot技术,揭示了ARL4D在结直肠癌中通过激活Wnt/β-catenin通路促进肿瘤转移和干性特征的分子机制。

2. **文献名称**: *Structural characterization of ARL4D and its interaction with effector proteins*

**作者**: Chen L, Wang H, et al.

**摘要**: 通过ARL4D抗体进行免疫共沉淀(Co-IP)和质谱分析,研究发现ARL4D的晶体结构及其与细胞骨架调控蛋白(如IQGAP1)的相互作用,阐明其在细胞极性建立中的作用。

3. **文献名称**: *ARL4D deficiency ameliorates hepatic steatosis by suppressing lipogenesis*

**作者**: Kim S, Park JH, et al.

**摘要**: 使用ARL4D敲除小鼠模型及抗体检测,发现ARL4D通过调控SREBP1c通路促进肝脏脂质合成,其抗体在脂肪肝病理模型中的应用为代谢性疾病提供了潜在治疗靶点。

---

**备注**:以上文献信息为示例,实际文献需通过PubMed或Google Scholar以关键词“ARL4D antibody”或“ARL4D function”检索确认。若需具体文献链接或补充年份/期刊信息,可进一步提供。

       

背景信息

The ARL4D (ADP-ribosylation factor-like 4D) protein belongs to the ARF/ARL family of small GTPases, which regulate intracellular trafficking, cytoskeletal dynamics, and signaling pathways. ARL4D shares structural homology with other ARL proteins but exhibits distinct functional roles, particularly in membrane remodeling, vesicle transport, and cell migration. Studies suggest its involvement in developmental processes, cancer progression, and neurological disorders, though its precise mechanisms remain under investigation.

ARL4D antibodies are critical tools for detecting and characterizing the expression, localization, and interaction partners of ARL4D in biological samples. They are widely used in techniques like Western blotting, immunofluorescence, and co-immunoprecipitation to explore its role in cellular processes. Research has linked ARL4D dysregulation to cancers (e.g., colorectal, glioblastoma) and neurodevelopmental conditions, potentially through interactions with Wnt or Hedgehog signaling pathways.

Current challenges in ARL4D research include understanding its isoform-specific functions, post-translational modifications, and crosstalk with related proteins like ARL4C/ARL4A. Antibody specificity remains crucial, as high sequence similarity among ARL family members can lead to cross-reactivity. Despite these hurdles, ARL4D antibodies continue to facilitate insights into its therapeutic potential, particularly in targeting aberrant GTPase activity in disease contexts. Further studies are needed to validate its clinical relevance as a biomarker or drug target.

       
关键字: ARL4D抗体;ARL4D;ARL4D Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
询盘

ARL4D抗体—艾普蒂相关厂家报价

产品名称 价格   公司名称 报价日期
¥1950
VIP4年
上海沪震实业有限公司
2026-02-09
询价
上海华盈生物医药科技有限公司
2026-02-15
询价
VIP4年
维百奥(北京)生物科技有限公司
2025-12-29
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.