C19orf57抗体,Rabbit Polyclonal C19orf57 Antibody
  • C19orf57抗体,Rabbit Polyclonal C19orf57 Antibody
  • C19orf57抗体,Rabbit Polyclonal C19orf57 Antibody
  • C19orf57抗体,Rabbit Polyclonal C19orf57 Antibody

C19orf57抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-21
QQ交谈 微信洽谈

产品详情

中文名称:C19orf57抗体英文名称:Rabbit Polyclonal C19orf57 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 5290 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: C19orf57
2025-05-21 C19orf57抗体 Rabbit Polyclonal C19orf57 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 5290 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/40-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

WB Predicted band size70 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFusion protein of human C19orf57
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: PC3 cell lysate, Primary antibody: P10101(C19orf57 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P10101(C19orf57 Antibody) at dilution 1/50. (Original magnification: ×200)    


           

参考文献

以下是关于C19orf57抗体的3篇参考文献示例(注:内容为虚构,仅供格式参考):

1. **文献名称**:*C19orf57 regulates mitochondrial RNA metabolism and its deficiency causes developmental defects*

**作者**:Smith J, Lee K, et al.

**摘要**:本研究通过C19orf57抗体进行免疫印迹和免疫荧光实验,发现C19orf57蛋白定位于线粒体,参与线粒体RNA的加工。基因敲除小鼠模型显示胚胎发育异常,提示其在细胞能量代谢中的关键作用。

2. **文献名称**:*Characterization of C19orf57 interaction with the ciliary transport machinery*

**作者**:Garcia R, Tanaka M, et al.

**摘要**:利用C19orf57特异性抗体进行免疫共沉淀和免疫组化分析,揭示了C19orf57与纤毛内运输蛋白IFT20的相互作用,表明其在纤毛形成和信号传导中的功能缺失可能导致先天性肾病。

3. **文献名称**:*C19orf57 expression correlates with glioma progression and patient survival*

**作者**:Chen L, Wang H, et al.

**摘要**:通过C19orf57抗体对胶质瘤组织进行免疫染色,发现其高表达与肿瘤恶性程度和患者不良预后显著相关,体外实验证实C19orf57通过调控细胞周期蛋白促进癌细胞增殖。

如需真实文献,建议通过PubMed或Google Scholar以“C19orf57 antibody”为关键词检索近期论文。

       

背景信息

The C19orf57 antibody is a valuable tool for studying the function and expression of the C19orf57 protein, encoded by the *C19orf57* gene located on human chromosome 19. This gene, also known as *FLJ22555* or *CIAO3*, encodes a conserved protein implicated in mitochondrial iron-sulfur (Fe-S) cluster assembly and ribosome biogenesis. Mutations in *C19orf57* are associated with genetic disorders such as combined oxidative phosphorylation deficiency (COXPD34), a severe mitochondrial disorder characterized by metabolic acidosis, encephalopathy, and early lethality. The C19orf57 protein interacts with components of the cytosolic iron-sulfur assembly (CIA) machinery, playing a role in cellular iron homeostasis and genome stability.

C19orf57 antibodies are widely used in research applications like Western blotting, immunofluorescence, and immunohistochemistry to detect protein expression levels, subcellular localization (primarily mitochondrial), and tissue distribution. These antibodies are typically generated using recombinant protein fragments or synthetic peptides as immunogens, with validation in knockout models to confirm specificity. Studies utilizing C19orf57 antibodies have advanced understanding of its involvement in mitochondrial dysfunction, metabolic diseases, and cancer, where altered expression may correlate with tumor progression. Commercial availability from multiple biotech vendors facilitates its use in both basic research and clinical investigations, aiding in biomarker discovery and mechanistic studies of Fe-S cluster-related pathologies.

       
关键字: C19orf57抗体;C19orf57;C19orf57 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
普通会员
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
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