The STK32B (serine/threonine kinase 32B) antibody is a tool used to study the STK32B protein, a member of the serine/threonine kinase family. STK32B, also known as YANK2. is implicated in cellular signaling pathways regulating processes like proliferation, differentiation, and apoptosis. Its exact biological functions remain under investigation, but studies suggest potential roles in neuronal development, tissue homeostasis, and cancer progression. The antibody enables detection and quantification of STK32B expression in various experimental models, facilitating research into its tissue-specific distribution, activation states, and interactions with downstream targets.
STK32B antibodies are commonly used in techniques such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to analyze protein expression patterns in cells, tissues, or biological fluids. Recent studies have explored STK32B's association with diseases, including neurodegenerative disorders and certain cancers, where dysregulated kinase activity may contribute to pathogenesis. Researchers also utilize these antibodies to investigate post-translational modifications or subcellular localization of STK32B, providing insights into its regulatory mechanisms. Validation of STK32B antibodies typically includes knockout controls, peptide blocking assays, and cross-reactivity tests to ensure specificity. As interest in kinase-targeted therapies grows, STK32B antibodies serve as critical reagents for both basic research and potential diagnostic applications.