EIF3G抗体,Rabbit Polyclonal EIF3G Antibody
  • EIF3G抗体,Rabbit Polyclonal EIF3G Antibody
  • EIF3G抗体,Rabbit Polyclonal EIF3G Antibody
  • EIF3G抗体,Rabbit Polyclonal EIF3G Antibody

EIF3G抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-21
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产品详情

中文名称:EIF3G抗体英文名称:Rabbit Polyclonal EIF3G Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 5559 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: EIF3G
2025-05-21 EIF3G抗体 Rabbit Polyclonal EIF3G Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 5559 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/150-1/300 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesEIF3S4; EIF3-P42; eIF3-p44; eIF3-delta
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human EIF3G
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P10475(EIF3G Antibody) at dilution 1/110. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P10475(EIF3G Antibody) at dilution 1/110. (Original magnification: ×200)    


           

参考文献

以下是关于EIF3G抗体的虚构参考文献示例(仅供格式参考):

1. **"EIF3G regulates cap-dependent translation and interacts with mTOR signaling in colorectal cancer"**

- Author: Zhang L, et al.

- 摘要:研究利用EIF3G抗体通过免疫沉淀和Western blot分析,揭示EIF3G在结直肠癌细胞中通过mTOR通路调控蛋白质翻译的机制,提示其作为潜在治疗靶点。

2. **"Development of a monoclonal antibody against EIF3G for detecting viral translation machinery hijacking"**

- Author: Kim S, et al.

- 摘要:报道一种新型EIF3G单克隆抗体的开发,验证其在检测RNA病毒(如HCV)劫持宿主翻译复合体中的特异性,为病毒感染机制研究提供工具。

3. **"EIF3G expression correlates with poor prognosis in glioblastoma multiforme"**

- Author: Patel R, et al.

- 摘要:通过免疫组化(使用EIF3G抗体)分析胶质母细胞瘤组织,发现EIF3G高表达与患者生存期缩短相关,提示其作为预后标志物的潜力。

4. **"Functional characterization of EIF3G in embryonic development using CRISPR/Cas9 and antibody-based assays"**

- Author: Müller J, et al.

- 摘要:结合CRISPR基因编辑和EIF3G抗体功能实验,证明EIF3G缺失导致小鼠胚胎发育中蛋白质合成障碍及细胞周期停滞。

注:以上文献为示例,实际引用需查询真实数据库(如PubMed)。

       

背景信息

EIF3G (eukaryotic translation initiation factor 3 subunit G) is a critical component of the eukaryotic initiation factor 3 (eIF3) complex, which plays a central role in initiating protein synthesis by facilitating ribosome assembly and mRNA recruitment during translation. As part of the multi-subunit eIF3 complex, EIF3G contributes to stabilizing the interaction between the 40S ribosomal subunit and initiator tRNA, as well as regulating the scanning and selection of start codons. The eIF3 complex is also implicated in post-transcriptional gene regulation, stress responses, and disease pathways, including cancer and viral infection.

Antibodies targeting EIF3G are essential tools for studying its expression, localization, and molecular interactions in both physiological and pathological contexts. These antibodies are widely used in techniques such as Western blotting, immunoprecipitation, immunofluorescence, and co-immunoprecipitation to investigate eIF3G’s role in translation initiation, its association with other eIF3 subunits, and its potential dysregulation in diseases. For example, studies have linked altered eIF3G expression to tumor progression, viral replication mechanisms, and neurological disorders, making it a biomarker of interest. Researchers also utilize EIF3G antibodies to explore post-translational modifications, such as phosphorylation, that modulate its function. Validated antibodies with high specificity are critical to ensure accurate detection, given the structural complexity of the eIF3 complex and sequence homology among subunits.

       
关键字: EIF3G抗体;EIF3G;EIF3G Antibody;

公司简介

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主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
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  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
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